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| 不同时期高容量血液滤过对严重创伤并发MODS预后的影响 | |
| 引用本文： | 汤锋,苟仲勇,尹昌林,周人杰,周巧巧. 不同时期高容量血液滤过对严重创伤并发MODS预后的影响[J]. 西南国防医药, 2011, 21(7): 701-704. DOI: 10.3969/j.issn.1004-0188.2011.07.002 |
| 作者姓名： | 汤锋 苟仲勇 尹昌林 周人杰 周巧巧 |
| 作者单位： | 1. 解放军452医院肾内科,成都,610021 2. 解放军452医院急诊科,成都,610021 3. 第三军医大学西南医院急救部 4. 第三军医大学新桥医院急救部 |
| 摘 要： | 目的探讨不同时期行高容量血液滤过（HVHF）对严重创伤并发多器官功能障碍综合征（MODS）预后的影响。方法将2006年1月～2011年1月行HVHF治疗的72例严重创伤并发MODS的患者分为对照组35例和治疗组37例，对照组采用一般治疗的方法，治疗组采用HVHD的方法。再用AKIN标准将治疗组分为A组（AKI 1期）、B组（AKI2期）、C组（AKI3期），观察对照组和治疗组30d时的病死率；观察两组人组时和治疗24h后的APACHEⅡ评分、SOFA评分、血浆IL-6、氧合指数、血肌酐（cr）变化情况。结果（1）治疗组30d的病死率低于对照组（46％VS71％，P〈0．05）。（2）人组24h后治疗组的APACHEⅡ评分、SOFA评分、IL-6、Cr均低于对照组，氧合指数高于对照组（P〈0．05）。（3）A、B、C3组治疗后的APACHEⅡ评分、SOFA评分、IL-6、Cr均下降，氧合指数升高，AKI分期越早越明显。结论HVHF能有效辅助治疗严重创伤并发MODS；AKIN标准及IL-6对判断预后有指导意义；早期（AKI1期和2期）行HVHF可明显改善严重创伤并发MODS的预后，而AKI 1期行HVHF的疗效更好。 |
| 关 键 词： | 高容量血液滤过 创伤 多器官功能障碍综合征 预后 AKI |
Prognostic effects of high - volume hemofiltration at different phases of acute kidney injury on severe trauma complicated with multiple organ dysfunction syndrome |
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| Tang Feng,Gou Zhongyong,Yin Changlin,Zhou Renjie,Zhou Qiaoqiao. Prognostic effects of high - volume hemofiltration at different phases of acute kidney injury on severe trauma complicated with multiple organ dysfunction syndrome[J]. Medical Journal of National Defending forces in Southwest China, 2011, 21(7): 701-704. DOI: 10.3969/j.issn.1004-0188.2011.07.002 | |
| Authors: | Tang Feng Gou Zhongyong Yin Changlin Zhou Renjie Zhou Qiaoqiao |
| Affiliation: | Tang Feng1,Gou Zhongyong2,Yin Changlin3,Zhou Renjie4,Zhou Qiaoqiao1 1.Department of Nephrology,2.Emergency Department,Hospital 452 of PLA,Chengdu,Sichuan,610021,China,3.Emergency Department,Southwest Hospital of Third Military Medical University,Chongqing,430038,4.Emergency Department,Xinqiao Hospital of Third Military Medical University,430037 |
| Abstract: | Objective To investigate prognostic effects of high-volume hemofiltration(HVHF)at different phases of acute kidney injury(AKI)on severe trauma complicated with multiple organ dysfunction syndrome(MODS).Methods Clinical data of 72 patients with severe trauma complicated with MODS receiving HVHF from January 2006 to January 2011 were retrospectively studied.They were divided into control group(n=35)and treatment group(n=37).Patients in control group were treated by common therapies,while those in treatment gr... |
| Keywords: | AKI |
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