| 奥卡西平治疗癫(癎)部分性发作的疗效观察 |
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| 引用本文： | 戴加飞,李倩,刘玲,张申宁,程茅薇,孔丽,陈光辉,杨昉. 奥卡西平治疗癫(癎)部分性发作的疗效观察[J]. 临床神经病学杂志, 2011, 24(2) |
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| 作者姓名： | 戴加飞 李倩 刘玲 张申宁 程茅薇 孔丽 陈光辉 杨昉 |
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| 作者单位： | 南京军区南京总医院神经内科,210002 |
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| 摘 要： | 目的:观察奥卡西平治疗癫癎部分性发作的疗效.方法:51例部分性发作的癫癎患者采用奥卡西平治疗.成年患者起始剂量300mg/d,根据病情逐渐加量,3d后增至基本维持量(600mg/d),仍有发作者继续加量,2周后达最佳效果或可耐受的最高剂量(1800mg/d);儿童患者起始剂量8-10mg/(kg·d),根据病情每周加1次剂量,每次加量不超过10 mg/(kg·d),直至维持剂量30-40mg/(kg·d).观察治疗后癫癎发作情况及药物不良反应.结果:奥卡西平治疗5个月后,本组患者总有效率为74%,完全控制率为30%.用药1个月内,本组7例患者出现不良反应,1例因全身皮疹停用奥卡西平.结论:奥卡西平治疗癫癎部分性发作的疗效较好,但有时可产生较严重不良反应,临床应用须谨慎.
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| 关 键 词： | 癫(癎) 部分性发作 奥卡西平 疗效 |
Observation of the curative effects of Oxcarbazepine on treating partial seizures |
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| DAI Jia-fei,LI Qian,LIU Ling,et al.. Observation of the curative effects of Oxcarbazepine on treating partial seizures[J]. Journal of Clinical Neurology, 2011, 24(2) |
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| Authors: | DAI Jia-fei LI Qian LIU Ling et al. |
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| Affiliation: | DAI Jia-fei,LI Qian,LIU Ling,et al.Department of Neurology,General Hospital of Nanjing Military Command,Nanjing 210002,China |
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| Abstract: | Objective To observe the curative effects and the safety of Oxcarbazepine on treating partial seizures.Methods Fifty-one patients with partial seizures were treated with Oxcarbazepine.The first dosage of adults was 300 mg/d,and it grew up with the progress of the disease.The dosage got normal stage(600 mg/d) at 3 d later.If then still can not control the seizures,the dosage could keep growing until the best effect or the highest dosage(1800 mg/d) at 2 weeks later.The first dosage of children was 8-10 mg/(kg... |
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| Keywords: | epilepsy partial seizures Oxcarbazepine curative effects |
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