MRI对肥厚型心肌病左右心室整体功能变化的研究

目的利用磁共振电影成像技术探讨肥厚型心肌病患者左、右心室整体功能的变化。材料与方法连续收集自2013年2月至2014年2月在我院行心脏核磁共振检查的被拟诊为肥厚型心肌病的患者共26例,同期收集20例健康志愿者心脏核磁共振检查的图像。由两名放射科医师分别将26例肥厚型心肌病患者和20例健康志愿者的图像导入Report CARD3.6心脏功能分析软件进行相关数据测量,最终获得左、右心室的舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)、每搏输出量(SV)以及左心室的短轴缩短率(FS)。肥厚型心肌病患者与健康志愿者之间左、右心室功能指标的比较采用独立样本t检验。结果肥厚型心肌病患者左心室整体功能的各项指标LVEDV、LVESV、LVEF、LVSV及FS分别为(88.94±13.29)ml、(24.75±7.31)ml、(71.70±7.60)%、(64.20±12.82)ml、(52.52±8.83)%,健康志愿者LVEDV、LVESV、LVEF、LVSV及FS分别为(107.93±12.62)ml、(34.18±3.6)ml、(67.25±4.48)%、(73.65±12.41)ml、(36.8±3.82)%,LVEDV、LVESV、LVSV数值较健康志愿者均减低,二者之间有显著性差异;LVEF较正常人增高,但没有显著性差异;FS较正常人显著增高,二者之间有显著性差异。肥厚型心肌病患者右心室整体功能各项指标RVEDV、RVESV、RVEF、RVSV分别为(88.48±17.67)ml、(29.84±7.50)ml、(6 4.6 5±1 0.2 7)%、(5 8.6 6±1 7.0 9)m l,健康志愿者RV E D V、RV E S V、RVEF、RVSV分别为(142.31±23.62)ml、(72.49±16.13)ml、(49.18±5.6)%、(69.82±13.43)ml,RVEDV、RVESV较正常人明显减低,二者之间有显著性差异;RVEF较正常人增高,二者之间有显著性差异;RVSV较正常人减低,二者之间没有显著性差异。结论在早期,肥厚型心肌病左心室舒张功能减低、收缩功能升高的同时,右心室的舒张功能也减低、收缩功能升高,左右心室的功能变化是一致的。

Study of magnetic resonance imaging in the evaluation of left and right global function of patients with hypertrophic cardiomyopathy

AbstractObjectives:To evaluate the global function of the left and right ventricle using MRI in the patients with hypertrophic cardiomyopathy. Materials and Methods:Twenty-six patients who were diagnosed with hypertrophic cardiomyopathy were collected. All the patients and twenty volunteers were performed cardiac magnetic resonance. All the images were analyzed by two radiologists using the software of ReportCARD3.6. The end-diastolic volume(EDV), end-systolic volume(ESV), stroke volume(SV) , ejection fraction(EF) and fractional shortening(FS) were acquired. The global function of the left and right ventricle of patients and volunteers were compared with independent-samplet test.Results:Respectively, the left EDV、ESV、EF、SV and FS of patients’were (88.94±13.29) ml、(24.75±7.31) ml、(71.70±7.60) %、(64.20±12.82) ml、(52.52±8.83) %, respectively, the left EDV、ESV、EF、SV
and FS of volunteers’were (107.93±12.62) ml、(34.18±3.6) ml、(67.25±4.48) %、(73.65±12.41) ml、(36.8±3.82) %, EDV、ESV、SV were lower than that of volunteers, there is signiifcant difference between the two groups; EF was higher than that of volunteers, but there is no signiifcant difference between the two groups; FS were higher than that of volunteers, there is signiifcant difference between the two.Respectively, the right EDV、ESV、EF、SV of patients’were (88.48±17.67) ml、(29.84±7.50) ml、(64.65±10.27) %、(58.66±17.09) ml, respectively, the right EDV、ESV、EF、SV of volunteers’were(142.31±23.62) ml、(72.49±16.13) ml、(49.18±5.6) %、(69.82±13.43) ml, EDV、ESV were lower than that of volunteers, there is signiifcant difference between the two groups;EF was higher than that of volunteers, there is signiifcant difference between the two; SV is lower than that of volunteers, there is no significant difference between the two.Conclusions:The change of left and right ventricular were similar. To hypertrophic cardiomyopathy patient, the left ventricle diastolic function decrease and the systolic function increase in the early time. Meanwhile, the right ventricle diastolic function decrease and the systolic function increase.