阿霉素、顺铂为主的联合化疗治疗卵巢恶性肿瘤

1988年11月至1993年2月共收治卵巢恶性肿瘤19例，其中复发性卵巢癌9例，卵巢转移癌10例。采用以阿霉素、顺铂为主的联合化疗方案，15例有腹水者经上述治疗后，显效4例，有效9例，客观有效率为86.7％；9例复发性卵巢癌化疗后完全缓解6例、部分缓解1例，有效率为77.8％。其中3例再次手术后辅以化疗，生存时间延长，1例已存活4年余。全组未发生严重地毒副作用。治疗结果显示，以阿霉素、顺铂为主的联合化疗方案对复发性和卵巢转移癌不失为一有效的治疗方法。

Cisplatin and Adriamycin Combination Chemotherapy for Advanced Ovariocarcinoma

19 patients with advanced ovariocarcinoma were treated during Novermber 1988 to February 1993.In these cases,9 had recurrent ovariocarcinoma and 10 had metastatic ovariocarcinma.They were given the regimen of combination chemotherapy of cisplatin (DDP) and Adriamycin (ADM).Among the 15 patients with ascites,the remarkable efffects in controlling malignant ascites were gained in 4 cases and ascites reduction was noted in 9 cases.The overall responsece rate was 86.7%.In 9 cases with recurrence the overall response rate was 77.8%,with 6 patients having complete remmision and 1 patient achiving partial remmision.In second group 3 patients received second operation. In all of these patients,no remarkable toxicity reaction was observed and the survival time was prolonged.One patient has survived for 4 years.The results indicate that the combination chemotherapy of DDP and ADM is a effective regimen for advanced recurrent and inetastatic ovariocarcinoma.