代谢综合征178例辨证分型及相关性研究

目的:研究代谢综合征(MS)患者的中医辨证分型与体重指数、瘦素等指标的相关性。方法:收集178例代谢综合征病人的临床资料,辨证分为4种证型:气滞湿阻证、痰瘀互地证、气阴两虚证、脾肾气虚证,对相关资料进行研究。结果:气滞湿阻型及痰瘀互结型患者所占比例明显高于其他两个证型,其他两证所占比例相似。痰瘀互结证的腹围及体重指数明显高于其他三证,而气滞湿阻证又高于气阴两虚证及脾肾气虚证。气滞湿阻证和痰瘀互结证的TC、LDL-C、INS、2hINS和瘦素均明显高于其他二证。结论:气滞湿阻型及痰瘀互结型患者所占比例明显高于其他两个证型。气滞湿阻证和痰瘀互结证的胆固醇升高更为明显,胰岛素抵抗更加严重,且由脂肪细胞分泌的瘦素升高更多。

Differentiation for Classification of Syndrome for Metabolic Syndrome and Their Associativity, A Report of 178 Cases

Objective ： To study the associativity between differentiation of symptoms and signs for classification of syndrome and BMI and LEP in the patients with metabolic syndrome. Methods： The clinical data of 178 cases with metabolic syndrome were collected and divided into four patterns of syndrome, which were syndrome of reten- tion of dampness due to stagnation of qi, syndrome of tangle of phlegm and blood stasis, syndrome of deficiency of qi and yin, and syndrome of deficiency of qi of spleen and kidney. Then they were analyzed and studied. Results ： The proportions of syndrome of retention of dampness due to stagnation of qi and syndrome of tangle of phlegm and blood stasis were higher than those of the other two syndromes. Syndrome of deficiency of qi and yin and syndrome of deficiency of qi of spleen and kidney had the same proportions. The abdomen circumference and BMI in syn- drome of tangle of phlegm and blood stasis were higher than those of the other three syndromes, and those in syn- drome of retention of dampness due to stagnation of qi were higher than those in syndrome of deficiency of qi and yin and syndrome of deficiency of qi of spleen and kidney. TC, LDL-C, INS, 2hINS and LEP in syndrome of re- tention of dampness due to stagnation of qi and syndrome of tangle of phlegm and blood stasis were higher remark- ably than those in the other syndromes. Conclusion： The proportions of syndrome of retention of dampness due to stagnation of qi and syndrome of tangle of phlegm and blood stasis were higher than those of the other two syn- dromes. Cholesterin increases more markedly in syndrome of retention of dampness due to stagnation of qi and syn- drome of tangle of phlegm and blood stasis. So is insulin resistance （ IR）, which is more serious, and LEP secre- ted by adipose increases higherly more.