脂肪性肝病与胃食管反流病的相关性研究

目的评估脂肪性肝病(FLD)与胃食管反流病GERD之间的关系。方法选取2 000例受试者,采用较简便的胃食管反流病问卷(GerdQ)作为初筛GERD诊断标准,对入选者均进行腹部超声波等检查,分析FLD与GERD关系。结果对2 000例患者利用GerdQ评估GERD诊断情况,有176例(8.8%)诊断为GERD,女68人(38.64%),男108人(61.36%);脂肪肝患者760例,患病率38.0%,在脂肪肝组中,男女性GERD症状的GerdQ阳性率分别为13.77%和12.24%,两者无明显差异(P>0.05)。脂肪肝人群发生GERD症状的患病率与对照组存在统计学差异(P<0.05)。结论脂肪肝与GERD显著相关,控制脂肪肝发展可以降低GERD发病率。

Study on the relationship between fatty liver disease and gastroesophageal reflux disease

Objective To evaluate the relationship between fatty liver disease(FLD) and gastroesophageal reflux disease(GERD).Methods 2 000 people were chosen to screen GERD according to a simple gastroesophageal reflux disease questionnaire(GerdQ),patients with GERD were performed abdomen ultrasonography and other examinations.Based on above examination results,relationship between FLD and GERD was analyzed.Results The result indicated that 176 cases(8.8%) were found GERD in the 2 000 cases according to GerdQ.Among 176 subjects,female was 38.64%,male was 61.36%.Among 2 000 subjects,760(38.0%) were diagnosed as FLD.Among the FLD patients,female with GERD was 12.24%,male with GERD was 13.77%(P>0.05).And there were statistic significances in prevalence of fatty liver between GERD group and control group(P<0.05).Conclusion There is a significant correlation between fatty liver disease and GERD,and control fatty liver’s development can reduce the incidence of GERD.