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小鼠肿瘤浸润淋巴细胞联合放疗对小鼠宫颈癌U_(14)的治疗作用
引用本文:廖贵清 毛祖彝. 小鼠肿瘤浸润淋巴细胞联合放疗对小鼠宫颈癌U_(14)的治疗作用[J]. 华西口腔医学杂志, 1997, 15(3): 0-259
作者姓名:廖贵清 毛祖彝
作者单位:华西医科大学口腔医学院口腔颌面外科
摘    要:利用Rosenberg实验室建立的肿瘤浸润淋巴细胞(TIL)制备方法对小鼠宫颈癌TIL进行分离培养,在建立小鼠宫颈癌U14移植瘤的基础上,用TIL联合局部放疗治疗,观察抗瘤作用。结果发现小鼠TIL及放疗对小鼠宫颈癌U14均有较好的抑制生长作用,二者联合使用,其抑瘤作用更强,E/O值为1.1。提示,TIL治疗与放疗存在相加关系。

关 键 词:小鼠  TIL  宫颈癌
收稿时间:1997-06-25

Antitumor Effect of TIL Combined with Radiotherapy on Mouse Uterocervical Cancer U 14
Liao Guiqing,Mao Zuyi,Xu Pingping. Antitumor Effect of TIL Combined with Radiotherapy on Mouse Uterocervical Cancer U 14[J]. West China journal of stomatology, 1997, 15(3): 0-259
Authors:Liao Guiqing  Mao Zuyi  Xu Pingping
Affiliation:Department of Oral & Maxillofacial Surgery, College of Stomatology.
Abstract:After yielding culturing mouse TIL from U 14 with Rosenberg's technique, the authors observed the antitumor effect of TIL combined with radiotherapy on established mouse transplanted tumor of uterocervical cancer U 14 . The results demonstrated TIL treatment or radiotherapy could inhibit the tumors growth. Combination showed a stronger inhibition and the E/O value was 1.1. It implied that an additive effect was gotten when conbining TIL with radiotherapy.
Keywords:mouse TIL uterocervical cancer radiotherapy
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