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Prevention of febrile nonhemolytic transfusion reaction with leucocyte filtrated concentrates
作者姓名:赵树铭  向国春
作者单位:[1]DepartmentofTransfusionMedicine,SouthwestHospital,ThirdMilitaryMedicalUniversity,Chongqing400038,China [2]Gastroenterology,SouthwestHospital,ThirdMilitaryMedicalUniversity,Chongqing400038,C
摘    要:Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosis, gastric ulcer or cancer were subjected to receive RBC concentrates after leucocyte filtration. Another 50 patients with similar diseases were selected to receive non-filtrated RBC concentrates. The incidence of FNHTRs in all patients was investigated. Results: There was no FNHTR in 100 transfusions with leucocyte filtrated RBC concentrates, while FNHTRs occurred in 8 of 50 patients with non-filtrated RBC concentrates, with the incidence of 16%. Conclusion: FNHTRs to RBC transfusion can be prevented with leucocyte filtration.

关 键 词:白细胞过滤  发热性非溶血性输血反应  输血

Prevention of febrile nonhemolytic transfusion reaction with leucocyte filtrated concentrates
ZHAO Shu-ming,XIANG Guo-chun,ZHANG Jia-si,CHENG Xiao-ling,LI Ru-qing.Prevention of febrile nonhemolytic transfusion reaction with leucocyte filtrated concentrates[J].Journal of Medical Colleges of PLA(China),2002,17(1):54-55.
Authors:ZHAO Shu-ming  XIANG Guo-chun  ZHANG Jia-si  CHENG Xiao-ling  LI Ru-qing
Abstract:Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosis, gastric ulcer or cancer were subjected to receive RBC concentrates after leucocyte filtration. Another 50 patients with similar diseases were selected to receive non-filtrated RBC concentrates. The incidence of FNHTRs in all patients was investigated. Results: There was no FNHTR in 100 transfusions with leucocyte filtrated RBC concentrates, while FNHTRs occurred in 8 of 50 patients with non-filtrated RBC concentrates, with the incidence of 16%. Conclusion: FNHTRs to RBC transfusion can be prevented with leucocyte filtration.
Keywords:leucocyte filtration  febrile nonhemolytic transfusion reaction  transfusion
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