| 低剂量电离辐射对松果腺调节睾丸酮的影响 |
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| 引用本文： | 李啸峰,马琳,张铭,迟宝荣. 低剂量电离辐射对松果腺调节睾丸酮的影响[J]. 吉林大学学报(医学版), 2002, 28(2): 161-162. DOI: 10.3969/j.issn.1671-587X.2002.02.018 |
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| 作者姓名： | 李啸峰 马琳 张铭 迟宝荣 |
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| 作者单位： | 1. 吉林大学第一医院消化内科,吉林,长春,130021;2. 吉林省肿瘤医院;3. 吉林大学神经内分泌研究所 |
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| 摘 要： | 目的:探讨低剂量X射线全身照射对小鼠松果腺调节睾丸酮(TS)的影响.方法:采用放免分析法检测低剂量电离辐射免疫兴奋效应的动物模型血清TS.结果:血清TS在照射后4 h开始升高,8 h达峰值(P＜0.01),12 h降至正常,24 h再次升高(P＜0.05),呈双峰变化趋势.结论:低剂量电离辐射可引起松果腺调节功能增强,进而引起下丘脑-垂体-性腺轴功能变化,TS水平升高.
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| 关 键 词： | 低剂量电离辐射 松果腺 睾丸酮 |
| 文章编号： | 1671-587X(2002)02-0161-02 |
| 修稿时间： | 2001-05-09 |
Effect of low dose radiation on pineal gland in regulation of serum testosterone level |
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| LI Xiao feng ,MA Lin ,ZHANG Ming ,CHI Bao rong. Effect of low dose radiation on pineal gland in regulation of serum testosterone level[J]. Journal of Jilin University: Med Ed, 2002, 28(2): 161-162. DOI: 10.3969/j.issn.1671-587X.2002.02.018 |
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| Authors: | LI Xiao feng MA Lin ZHANG Ming CHI Bao rong |
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| Affiliation: | LI Xiao feng 1,MA Lin 2,ZHANG Ming 3,CHI Bao rong 1 |
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| Abstract: | Objective: The effect of low dose radiation (LDR) on pineal gland in regulative function of testosterone (TS) in mice was determined in the study. Methods: The distribution of TS in the serum was analyzed by radioimmunoassay after WBI with 75 mGy X rays. Results:Since 4 h after WBI the TS levels of serum in mice increased up to its highest peak at 8 h ( P <0.001), then returned to the sham irradiation levels 12 h late,however, increased again after 24 h ( P <0 05), resulted in two peaks.Conclusion: The results indicated that whole body low dose radiation might stimulate the regulative function of pineal gland and sex gland, increasing the level of TS. |
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| Keywords: | low dose radiation pineal gland testosterone |
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