定期无偿献血对献血者血清铁和铁蛋白的影响

目的：研究献血对血清铁含量的影响。方法收集76例无偿献血人员为献血组，83例健康人员（非献血人员）为对照组，采集空腹静脉血，进行血常规、血清铁和铁蛋白检查。结果献血组血清铁、红细胞和红细胞压积均在正常范围，血清铁蛋白和血红蛋白除1例外也在正常范围。献血组男性血清铁蛋白为（116．52±67．16）ng／mL，对照组男性为（186．39±103．15） ng／mL，两组比较差异有统计学意义（P ＜0．05）；献血组女性血清铁蛋白为（66．2±47．62）ng／mL，对照组女性为（101．1±73．89） ng／mL，两组比较差异有统计学意义（P ＜0．05）。献血组血清铁与对照组比较差异无统计学意义（P ＞0．05）。结论献血组血清铁蛋白降低，但是并没有造成贫血。因此，献血可以减少体内的铁贮存量。

Effect of whole blood donation on serum iron and ferritin

Objective To study the influence of blood donation serum iron levels.Methods 76 blood donors and 83 control subjects (who had never donated blood)were enrolled to this study.Venous blood samples were drawn for Hb,RBC,HCT,serum iron and ferritin analysis.Results Serum ferritin and Hb of enrolled donors except one were above the mandatory threshold.Serum iron,RBC and HCT of enrolled donors were all above the mandatory threshold.Furthermore,we found that serum ferritin of male blood donors(116.52±67.16 ng/mL)were significantly lower than that of control subjects (186.39±103.15 ng/mL),and serum ferritin of female blood donors(66.2±47.62 ng/mL)were significantly lower than that of control subjects(101.1±73.89 ng/mL). In contrast,there was no difference of serum iron between blood donors and control group.Conclusion Anemia had not occurred in enrolled donors,but serum ferritin level decreased.Thus,whole blood donation could diminish iron stores.