| 肾综合征出血热并发肝损害453例临床分析 |
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| 引用本文： | 王九平,王平忠,李军,魏欣,王临旭,王雅格,张颖,何文革. 肾综合征出血热并发肝损害453例临床分析[J]. 肝脏, 2008, 13(1): 14-16 |
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| 作者姓名： | 王九平 王平忠 李军 魏欣 王临旭 王雅格 张颖 何文革 |
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| 作者单位： | 第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038;第四军医大学唐都医院全军感染病诊疗中心,西安,710038 |
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| 摘 要： | 目的探讨肾综合征出血热（HFRS）合并肝损害的临床特点及其规律性。方法对453例各期HFRS患者的肝功能及相关指标进行回顾性分析。结果各期HFRS患者均伴有肝损害，转氨酶轻度增高居多，γ-谷氨酰转肽酶（GGT）早期轻到中度升高，总胆红素仅轻度升高，碱性磷酸酶变化不明显。轻型、中型肾综合征出血热并发肝损害较少，重型、危重型多并发肝损害。结论肾综合征出血热早期即可并发肝损害，发生率较高，以转氨酶及GGT轻至中度增高为特征。不同类型HFRS患者肝损害程度与临床表现成正相关。肾综合征出血热病程中动态观察肝功能的变化有助于判断病情和预后。
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| 关 键 词： | 肾综合征出血热 肝损害 临床特点 |
| 收稿时间： | 2007-11-06 |
| 修稿时间： | 2007-11-06 |
Clinical analysis of 453 hemorrhagic fever with renal syndrome patients complicated with liver damage |
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| WANG Jiu-ping,WANG Ping-zhong,LI Jun,WEI Xin,WANG Lin-xu,WANG Ya-ge,ZHANG Ying,HE Wen-ge. Clinical analysis of 453 hemorrhagic fever with renal syndrome patients complicated with liver damage[J]. Chinese Hepatology, 2008, 13(1): 14-16 |
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| Authors: | WANG Jiu-ping WANG Ping-zhong LI Jun WEI Xin WANG Lin-xu WANG Ya-ge ZHANG Ying HE Wen-ge |
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| Affiliation: | WANG Jiu-ping WANG Ping-zhong LI Jan WEI Xin WANG Lin-xu WANG Ya-ge ZHANG Ying HE Wen-ge.The Center of Diagnosis , Treatment of Infectious Diseases of Chinese PLA,Tangdu Hospital,Fourth Military Medical University,Xi'an,710038,China |
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| Abstract: | Objective To investigate the clinical characteristics and regularities of liver damage in patients of hem- orrhagic fever with renal syndrome (HFRS).Methods A retrospective analysis of liver function test was taken in 453 pa- tients with HFRS.Results Liver damage could be seen in different stages of HFRS.Most of the HFRS patients with liver damage presented with mild increase of alanine aminotransferase(ALT)and aspartate aminotransferase (AST) (92. 56%),and mild increase of total bilirubin levels (94.15%).W... |
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| Keywords: | Hemorrhagic fever with renal syndrome Liver injury Clinical character |
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