Pneumococcal purpura fulminans successfully treated with activated protein C |
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Authors: | Minhas Khalid M Bashir Shahida Sarwari Arif R Parker John |
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Institution: | Department of Medicine, West Virginia University, Morgantown, WV 26506, USA. kminhas@med.miami.edu |
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Abstract: | Evidence suggests that sepsis is a systemic inflammatory condition complicated by dysequilibrium in coagulation and fibrinolytic homeostasis, with a shift in the balance towards increased coagulation over fibrinolysis. Protein C is a natural anticoagulant consumed and inactivated during sepsis. We present the case of a 33-year-old female, postsplenectomy, with pneumococcal sepsis and purpura fulminans, successfully treated with activated protein C. |
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