64层螺旋CT检测合并糖尿病的心绞痛病人冠脉粥样硬化斑块特点

目的:探讨64层螺旋CT检测心绞痛合并糖尿病患者脉粥样硬化斑块特点及应用价值。材料与方法:选取40例合并有糖尿病的心绞痛患者(合并糖尿病组)与40例未合并糖尿病的心绞痛患者(对照组),进行64层螺旋CT冠状动脉造影检查,分析结果。结果:冠状动脉粥样硬化斑块检出率、病变血管所在位置、血管面积、管腔面积、斑块面积方面两组比较差异无统计学意义(P0.05),合并糖尿病患者混合斑块占55.00%明显高于对照组的25.00%,斑块负荷为(65.88±20.47)%明显高于对照组的(54.32±19.85)%,两组比较差异具有统计学意义(P0.05);Logistic回归分析结果显示合并有糖尿病时患者混合斑块明显存在增多趋势(P0.05)、斑块负荷明显较高(P0.05),而软斑块与钙化斑块则与是否合并有糖尿病无关(P0.05)。结论:64层螺旋CT冠状动脉造影检查结果显示合并糖尿病的心绞痛患者较未合并糖尿病的心绞痛患者冠状动脉粥样硬化斑块以混合斑块多见、斑块负荷较高,提示合并糖尿病的心绞痛患者发生心血管意外的风险性更高。

64-slice Spiral CT in Detecting Diabetic Patients with Angina Pectoris of Coronary Atherosclerotic Plaque Characteristics

Purpose： To investigate the 64-slice spiral CT in detecting angina patients with diabetes mellitus atherosclerosis plaque characteristics and application value. Materials and Methods： 40 cases of patients with angina pectoris associated with diabetes（ diabetic group） and 40 cases of diabetic patients with angina pectoris not（ control group）,with64-slice CT coronary angiography,the analysis results. Results： of coronary atherosclerotic plaque detection rate,lesion location,vessel area,lumen area,plaque area was no difference between the two groups was statistically significant（ P〈0. 05）,mixed plaque in patients with diabetes accounted for 55. 00 % significantly higher than 25. 00%,plaque burden was（ 65.88 ± 20.47） % significantly higher than that（ 54.32 ± 19.85） %,the difference was statistically significant（ P〈0. 05）; Logistic regression analysis the results showed that when patients with diabetes mellitus mixed plaque evident increasing trend（ P〈0. 05）,plaque burden was significantly higher（ P〈0. 05）,while the soft plaque and calcified plaque is independent of whether diabetes mellitus（ P〉0. 05）. Conclusion： 64-slice CT coronary angiography showed that diabetic patients with angina pectoris than non diabetic patients with coronary atherosclerotic plaques more common in mixed plaques,plaque burden higher,suggesting that occur in diabetic patients with angina higher risk of cardiovascular accidents.