颜面部针刺镇痛效应传入途径的实验形态学研究——(一)三叉神经一级传入纤维的投射

<正> 临床实践和实验性研究表明:颜面部针刺具有镇痛、抑制内脏牵拉反应和调整内脏功能等特点.当切断和封闭三叉神经(第二支)时,此类效应明显减弱或消失,它提示颜面部针刺镇痛和调整内脏效应是通过三叉神经传入中枢的.文献记载,颜面部痛觉与三叉神经尾侧脊束核有关。我们也曾部分损坏家兔的三叉神经尾侧脊束核,观察过在此核损坏前、后的针刺镇痛效应和内脏调整效应,结果显示:颜面部针刺镇痛和针刺对内脏调整效应有可能通过不同途径传至不同的中枢部位.因而,进一步研究三叉神经一级传入纤

AN EXPERIMENTAL MORPHOLOGICAL STUDY OF THE AFFERENT PATHWAY REGARDING THE EFFECT OF THE FACIAL ACUPUNCTURE ANALGESIA Ⅰ.THE CENTRAL PRCJECTONS OF THE TRIGEMINAL PRIMARY AFFERENT FIBERS

Following the total or partial transection of the trigeminalroot in the rabbit and the lesion of the trigeminal semilunar ganglion in the cat,the central trigeminal projections were studied by the anterograde degenerat- ing method.The degenerating fibers were distributed into the trigeminal root.the ascending and descending fasicles,the trigeminal spinal and principal sensory nucleus.The projections of the three peripheral trigem- inal branches were arranged in dorsoventral order in the root,fasicles. spinal and principal sensory nucleus as described in previous studies. In addition,the trigeminal primary afferent fibers also project into the solitary nucleus,the commissural nucleus of the vagus,the dorsolate- ral reticular formation of the medulla oblongata and into the posterolate- ral funiculus and the posterior horn of the upper 3 cervical segments of the spinal cord.A few of the degenerating fibers were found in the locus coeruleus,the nucleus raphe magnus,and the nucleus cuneatus lateralis. Finally.the functional significance of the trigeminal primary projec- tions to the spinal caudal trigeminal nucleus,the solitary nucleus and the medullary reticular formation in the acupuncture analgesia and in relieving visceral-pulling response was discussed.