Effects of anxiolytic agents on some immunologic parameters of the stressed rats |
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Authors: | Arushanian E B Baturina M V Beĭer E V Kuz'mina E M |
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Affiliation: | Pharmacology Department, State Medical Academy, Ministry of Public Health of the Russian Federation, ul. Mira 310, Stavropol, 355024 Russia. |
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Abstract: | Repeated stress under forced swim test conditions suppresses most of the immunological characteristics in rats. Diazepam and melatonin (both in a dose of 0.1 mg/kg), while not changing significantly the immunological state of intact animals, decrease the stress-induced shifts. The immunotropic effect of melatonin is much more pronounced than that of diazepam. |
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