急性脑梗塞与脑出血相关因素的对比研究

目的:探讨不同危险因素在脑卒中发生的情况及不同危险因素在脑梗死与脑出血间的差异。方法:将收治的卒中患者共408例,其中脑梗死281例,脑出血127例,均预先对各项资料进行编码,输入计算机数据库。所有患者均进行系统的临床和辅助检查,生化指标为集体测定,脑卒中诊断经过MRI或CT确诊。结果:1、高血压、吸烟是脑卒中最重要的危险因素。2、脑出血患者首诊舒张压(P=0．014)、缓解期舒张压(P=0．006)、HDL(P=0．034)、较脑梗塞患者高,其差别有统计学意义;其TC(P=0．047)、吸烟(P=0．007)、心脏病病史(P=0．020)、糖尿病病史(0．000)、卒中家族史(P=0．033)、心脏病家族史(P=0．040)较脑梗塞患者低或少,其差别有统计学差异。3、与脑梗塞相比,吸烟(OR=0. 226,95％CI=0．107—1．623)、糖尿病病史(OR=0．094,95％CI=0．023—2．401)、心脏病病史(OR=0．046,95％CI=0．236-0．905)对脑出血危险较小;高血压病史(OR=1．096,95％CI=0．542-0.895)是脑出血唯一危险因素。结论:高血压、吸烟是脑卒中最重要的危险因素;脑梗塞与脑出血的危险因素并不完全一致。

Risk factors in patients with cerebral infarction versus intracerebral hemorrhage

Aim: To estimate the frequency of various risk factors for overall stroke and to identify risk factors for cerebral infarction(CD versus intracerebral hemorrhage(ICH) of china. Methods; Data from 408 patients,consisting of 281 patients with CI and 127 patients with ICH, were taken hospitalization from Department of Neurology of Affiliated First Hospital of Ningxia Medical College from October 2004 to October 2006. were examined through clinical diagnosis and brain CT or MRI got final diagnosis. Systematic investigations were performed on each patient. Result: Hypertension and cigarette smoking were the most prominent factor for overall stroke followed by family history of hypertension. By multi-variate analysis, in the whole patients both man and woman, the factors significantly associated with ICH as opposed CI were history of hypertension (OR=1. 096,95%CI=0. S42-0. 895) and were not smoking (OR=0. 226,95%C1 =0.107 - 1. 623 ) , history of diabetes mellitus (OR=0. 094,95%CI =0. 023 - 2. 401 ) and history of heart disease (OR = 0. 046,95%CI=0. 236-0. 905) . Conclusions: Hypertension and cigarette smoking were the most prominent factor for o-verall stroke . The factors for ischemic and hemorrhagic stroke are not the same.