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Post‐chemotherapy Maturation in Supratentorial Primitive Neuroectodermal Tumors |
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| Authors: | Lucie Lafay‐Cousin Walter Hader Xing Chang Wei Robert Nordal Douglas Strother Cynthia Hawkins Jennifer A. Chan |
| Affiliation: | 1. Division of Pediatric Hematology Oncology and Bone Marrow Transplantation, Alberta Children's Hospital, , Calgary, Alberta, Canada;2. Division of Pediatric Neurosurgery, Alberta Children's Hospital, , Calgary, Alberta, Canada;3. Department of Pediatric Radiology, Alberta Children's Hospital, , Calgary, Alberta, Canada;4. Department of Radiation oncology, Tom Baker Cancer Center, , Calgary, Alberta, Canada;5. Department of Pathology, Hospital for Sick Children, , Toronto, Canada;6. Department of Pathology & Laboratory Medicine, University of Calgary, , Calgary, Alberta, Canada |
| Abstract: | Maturation in central nervous system embryonal tumors is an uncommon phenomenon that is mainly reported in the context of specific histological subgroups of medulloblastoma. In this report we describe two cases of histological maturation in patients with supratentorial primitive neuroectodermal tumor with strikingly different outcomes. We discuss the potential impact of such findings on treatment and outcome. |
| Keywords: | ETANTR ETMR maturation prognosis sPNET |