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EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy

Authors:	G. Roberts K. Beyer C. Bindslev‐Jensen V. Cardona A. Dubois G. duToit P. Eigenmann M. Fernandez Rivas S. Halken L. Hickstein A. Høst E. Knol G. Lack M. J. Marchisotto B. Niggemann B. I. Nwaru N. G. Papadopoulos L. K. Poulsen A. F. Santos I. Skypala A. Schoepfer R. Van Ree C. Venter M. Worm B. Vlieg–Boerstra S. Panesar D. de Silva K. Soares‐Weiser A. Sheikh B. K. Ballmer‐Weber C. Nilsson N. W. de Jong C. A. Akdis the EAACI Food Allergy Anaphylaxis Guidelines Group

Affiliation:	1. David Hide Asthma and Allergy Research Centre, St Mary's Hospital, , Isle of Wight, UK;2. Clinical and Experimental Sciences and Human Development and Health Academic Units, University of Southampton Faculty of Medicine, , Southampton, UK;3. NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, , Southampton, UK;4. Division of Paediatric Pneumology and Immunology, Charité University Hospital, , Berlin, Germany;5. Department of Dermatology and Allergy Centre, Odense University Hospital, , Odense, Denmark;6. Allergy Section, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, , Barcelona, Spain;7. Department of Pediatric Pulmonology and Pediatric Allergy, University Medical Center Groningen, University of Groningen and GRIAC Research Institute, , Groningen, the Netherlands;8. MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, , London, UK;9. Department of Paediatric Allergy, Guy's and St Thomas' NHS Foundation Trust, , London, UK;10. Department of Child and Adolescent, University Hospitals of Geneva, , Geneva, Switzerland;11. Allergy Department, Hospital Clinico San Carlos, , Madrid, Spain;12. Hans Christian Andersen Children's Hospital, Odense University Hospital, , Odense, Denmark;13. Department of (Paediatric) Dermatology and Allergology, University Medical Center Utrecht, , Utrecht, the Netherlands;14. Food Allergy and Anaphylaxis Research and Education (FARE), , McLean, VA, USA;15. University of Tampere, , Tampere, Finland;16. Allergy Department, 2nd Pediatric Clinic, University of Athens, , Athens, Greece;17. Center for Pediatrics and Child Health, Institute of Human Development, University of Manchester, , Manchester, UK;18. Allergy Clinic Copenhagen University Hospital at Gentofte, , Copenhagen, Denmark;19. Department of Pediatric Allergy, Division of Asthma, Allergy & Lung Biology, , King's College, London, UK;20. Immunoallergology Department, Coimbra University Hospital, , Coimbra, Portugal;21. Department of Rehabilitation and Therapies, Royal Brompton and Harefield NHS Foundation Trust, , London, UK;22. Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, , Lausanne, Switzerland;23. Academic Medical Center, University of Amsterdam, , Amsterdam, The Netherlands;24. Emma Children's Hospital, Academic Medical Center, University of Amsterdam, , Amsterdam, the Netherlands;25. Allergy & Respiratory Research Group, Centre for Population Health Sciences, University of Edinburgh, , Edinburgh, UK;26. The Evidence Centre, , London, UK;27. Enhance Reviews Ltd, , Wantage, UK;28. Evidence‐Based Health Care Ltd, , Edinburgh, UK;29. Allergy Unit, Department of Dermatology, University Hospital Zürich, , Zürich, Switzerland;30. Department of Clinical Science and Education, S?dersjukhuset, Karolinska Institutet and Sachs’ Children's Hospital, , Stockholm, Sweden;31. ErasmusMC, Internal Medicine, Section Allergology, , Rotterdam, the Netherlands;32. Swiss Institute of Allergy and Asthma Research (SIAF), University of Zürich;33. Christine Kühne–Center for Allergy Research and Education (CK‐CARE), , Davos, Switzerland

Abstract:	Food allergy can result in considerable morbidity, impact negatively on quality of life, and prove costly in terms of medical care. These guidelines have been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group, building on previous EAACI position papers on adverse reaction to foods and three recent systematic reviews on the epidemiology, diagnosis, and management of food allergy, and provide evidence‐based recommendations for the diagnosis and management of food allergy. While the primary audience is allergists, this document is relevant for all other healthcare professionals, including primary care physicians, and pediatric and adult specialists, dieticians, pharmacists and paramedics. Our current understanding of the manifestations of food allergy, the role of diagnostic tests, and the effective management of patients of all ages with food allergy is presented. The acute management of non‐life‐threatening reactions is covered in these guidelines, but for guidance on the emergency management of anaphylaxis, readers are referred to the related EAACI Anaphylaxis Guidelines.

Keywords:	anaphylaxis food allergy guidelines oral food challenge pediatrics

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