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TLR2 activation causes tachyphylaxis to β2‐agonists in vitro and ex vivo: modelling bacterial exacerbation
Authors:H. Alkhouri  N. N. Rumzhum  M. M. Rahman  M. FitzPatrick  M. de Pedro  B. G. Oliver  J. E. Bourke  A. J. Ammit
Affiliation:1. Faculty of Pharmacy, University of Sydney, , Sydney, NSW, Australia;2. Respiratory Pharmacology Laboratory, Department of Pharmacology and Therapeutics, Lung Health Research Centre, University of Melbourne, , Melbourne, Vic., Australia;3. Woolcock Institute of Medical Research, University of Sydney, , Sydney, NSW, Australia;4. Respiratory Pharmacology Laboratory, Department of Pharmacology, Monash University, , Melbourne, Vic., Australia
Abstract:
Keywords:adrenergic agonists  bacteria  beta‐2 adrenergic receptors  tachyphylaxis  toll‐like receptor 2
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