Identification of a new HLA-B*78 allele in a Hispanic family |
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| Authors: | Gaidulis L Krausa P Schaub B Senitzer D |
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| Affiliation: | Department of Hematology/Bone Marrow Transplantation, City of Hope Medical Center, Duarte, California, USA. |
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| Abstract: | A new B*78 variant, B*7804, was detected in three members of a Hispanic family. The novel B*78 sequence differs from B*78021 by two substitutions: T at nucleotide 527 (all other B*78s have A) and T at nucleotide 583 (all other B*78s have a C). Both nucleotide substitutions encode amino acid changes at codons 152 and 171, respectively. |
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| Keywords: | HLA-B *78 alleles HLA-B sequence-B*7804 sequencing based typing |
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