| 直流电场对鸡胚绒毛尿囊膜血管生成作用的研究 |
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| 引用本文： | 邵阳,王永堂,高洁,罗治斌.直流电场对鸡胚绒毛尿囊膜血管生成作用的研究[J].中国医学物理学杂志,2007,24(1):36-37,40. |
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| 作者姓名： | 邵阳 王永堂 高洁 罗治斌 |
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| 作者单位： | 1. 川北医学院,附属医院,四川,南充,637000
2. 第三军医大学,大坪医院野战外科研究所,重庆,400042 |
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| 基金项目： | 国家自然科学基金;军队杰出人才基金 |
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| 摘 要： | 目的：探讨直流电场（electric fields．EF）对血管生成的影响及作用机制。方法：于发育第8天的鸡胚绒毛尿囊膜（chick embryo chorioallantoic membrane，CAM）上植入明胶海绵载体，其中加载不同强度EF，计数长入载体的血管和载体内的微血管密度（microvascular densily．MVD）。结果：150mV／mm、200mV／mm组在CAM上长入载体边缘的血管数和MVD与对照组间的有显著差别（p〈0．01）。结论：强度为150mV／mm、200mV／mm的直流电场能促进CAM的血管生成。
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| 关 键 词： | 直流电场 血管生成 鸡胚绒毛尿囊膜 |
| 文章编号： | 1005-202X（2007）01-0036-02 |
| 收稿时间： | 2006-08-21 |
| 修稿时间： | 2006-08-21 |
Effect of Direct Electric Fields on Angiogenesis of CAM |
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| SHAO Yang,WANG Yong-tang,GAO Jie,LUO Zhi-bin.Effect of Direct Electric Fields on Angiogenesis of CAM[J].Chinese Journal of Medical Physics,2007,24(1):36-37,40. |
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| Authors: | SHAO Yang WANG Yong-tang GAO Jie LUO Zhi-bin |
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| Institution: | 1.Affiliated Hospital, North Sichuan Medical College, Nanchong Sichuan 637000, China; 2.Research Institute of Surgery, Daping Hospital, Third military Medical University, Chongqing 400042, China |
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| Abstract: | Objective: The study was to reveal the effect of direct electric fields on angiogenesis of chick embryo chorioallantoic membrane(CAM).Methods: Gelatin sponges were implanted on top of CAM,when chick embryos developed on the 8th day,vessels which towards gelatin and microvascular density(MVD) in gelatin were counted on the 12th day.Results: On CAM model,numbers of vessels at the sponge-CAM boundary and MVD were significantly different between group of 150 mV/mm,200 mV/mm and group of saline(p< 0.01).Conclusions: The study has shown that direct electric fields,150 mV/mm and 200 mV/mm,could promote the angiogenesis on CAM model. |
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| Keywords: | direct electric fields angiogenesis chick embryo chorioallantoic membrane |
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