Triterpenes and triterpenoid saponins from the leaves of Ilex kudincha |
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| Authors: | Zuo Wen-Jian Dai Hao-Fu Chen Jing Chen Hui-Qin Zhao You-Xing Mei Wen-Li Li Xian Wang Jin-Hui |
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| Institution: | School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, P.?R. China. |
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| Abstract: | One new triterpene, kudinchalactone A (1), and four new triterpenoid saponins, ilekudinchosides A-D (2- 5), were isolated from the leaves of Ilex kudincha C.?J. Tseng along with eight known triterpenoids. These new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectra. Compounds 2, 3, 12, and 13 showed antibacterial activities against Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA). |
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