《丙型肝炎防治指南 (2019年版)》重要更新要点

比较了《丙型肝炎防治指南(2019年版)》和以往《丙型肝炎指南》的更新要点。介绍了新的术语。重点强调了世界卫生组织提出的目标——2030年消除病毒性肝炎的公共卫生威胁。在预防部分,将对高危人群进行丙型肝炎病毒感染筛查作为预防的首要手段,强调治疗就是预防。在治疗方面,首先推荐无干扰素的泛基因型方案。还介绍了我国自主研发的直接抗病毒药物,介绍了多个特殊人群的抗病毒治疗方案,包括肝硬化失代偿、慢性肾脏疾病、儿童和青少年、合并慢性肾脏损伤、肝移植前后、合并HBV感染、治疗失败人群、急性丙型肝炎等。介绍了简化的治疗监测流程,特别提到在我国西南地区流行的基因3型。

Highlights of the guidelines of prevention and treatment for hepatitis C(2019 version)

The key points from the updated guideline of prevention and treatment for hepatitis C(2019 version)is compared with the previous hepatitis C guideline.A new terminology and the World Health Organization's goal of eliminating viral hepatitis as a public-health threat by 2030 are stressed.In the prevention section,the screening for hepatitis C virus infection in high-risk population is the primary means of prevention,emphasizing that treatment,is prevention.In the aspect of treatment,pangenotypic interferon-free scheme are initial recommendations.In addition,it also introduces our country independent research and development on direct-acting antiviral agents,and antiviral therapy schedule for many special populations,including decompensated liver cirrhosis,chronic kidney disease,children and adolescents combined with chronic kidney injury,HBV infection-before and after liver transplantation,treatment failure,and acute hepatitis C.A simplified on-treatment monitoring schedule,especially genotype 3 prevalent in Southwest part of our country is introduced.