基于代谢组学的中医证候研究

证候一直是中医药研究的核心问题,但证候的复杂性使其很难通过现代医学的还原论方法来阐释。代谢组学是新近发展起来的一种组学方法,因其具有整体、动态等特点,与中医思维不谋而合,因此被广泛应用于中医证候的研究,且已显示出一定的优势。

The Study of Syndromes of Traditional Chinese Medicine Based on the Technology of Metabonomics

Syndrome is always one of the core problems in the study of traditional Chinese medicine. However, the complexity of the syndrome makes it difficult to use modern medical pattern with the view of reductionist to explain. Metabolomics is a newly developed method of genomics. Because it is characterized with integrity and dynamism, metabolomics coincide with the thinking of traditional Chinese medicine. So it is widely used in syndrome reseach of traditional Chinese medicine, and it has shown some advantages. This paper introduces the study of syndromes of traditional Chinese medicine based on the technology of metabonomics, mainly including the study of application of metabonomics in animal models and clinical on syndromes of traditional Chinese medicine. This fully shows that the metabonomics have a great advantages and broad prospects in the research of traditional Chinese medicine.