| 中医药治疗慢性萎缩性胃炎的系统评价 |
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| 引用本文： | 黄宣,吕宾.中医药治疗慢性萎缩性胃炎的系统评价[J].世界华人消化杂志,2010,18(10). |
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| 作者姓名： | 黄宣 吕宾 |
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| 作者单位： | 浙江中医药大学附属第一医院消化内科,浙江省杭州市,310006 |
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| 摘 要： | 目的:系统评价中医药与西医治疗慢性萎缩性胃炎的疗效与安全性.方法:检索Cochrane图书馆、PubMed、OVID数据库和中国期刊网中与维普中文科技期刊全文数据库的英文和中文随机对照试验(RCT)文献,将Jadad积分≥3分高质量文章纳入研究,并提取纳入研究的特征信息.数据分析采用Revman软件,检验异质性,并根据异质性结果选择相应的效应模型.最后绘制漏斗图及Egger回归方程评定有无发表偏倚.结果:8项RCT,804例患者入选.与对照组相比,中医药组的总显效率(OR=4.17,95%CI:2.32-7.52)、总有效率(OR=5.79,95%CI:4.09-8.21)、病理学改善:萎缩(OR=5.06,95%CI:2.83-9.08)、肠化(OR=5.67,95%CI:2.74-11.73)、不典型增生(OR=4.72,95%CI:1.93-11.51)、不良反应发生方面(OR=0.20,95%CI:0.09-0.47),差异具统计学意义(均P<0.05).在中、西医治疗H.pylori方面,两组无统计学差异(OR=5.56,95%CI:0.55-56.67).中医药组与对照组在CAG治疗中总显效率、总有效率、H.pylori转阴率、病理改善情况(萎缩、肠化、不典型增生)的漏斗图均基本呈现下宽上窄左右对称的图形,线性回归常数项检验统计量表明无发表偏倚,P值分别为0.781、0.791、0.702、0.645、0.593及0.779.结论:中医药组对CAG的总显效率、总有效率、病理学改善等方面明显优于西医组,同时在不良反应发生率方面,中医药组明显低于西医组.
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| 关 键 词： | 慢性萎缩性胃炎 中医药疗法 Meta分析 |
Treatment of chronic atrophic gastritis with Chinese medicines:a systematic review |
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| Xuan Huang,Bin Lv.Treatment of chronic atrophic gastritis with Chinese medicines:a systematic review[J].World Chinese Journal of Digestology,2010,18(10). |
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| Authors: | Xuan Huang Bin Lv |
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| Institution: | Xuan Huang,Bin Lv,Department of Gastroenterology,the First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,Zhejiang Province,China |
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| Abstract: | AIM:To systematically evaluate the efficacy and safety of traditional Chinese medicines and Western medicines in the treatment of chronic atrophic gastritis.METHODS:The randomized clinical trials (RCTs) that compared the efficacy or safety of traditional Chinese medicines and Western medicines in the treatment of chronic atrophic gastritis were retrieved by searching Cochrane library,PubMed,OVID,CNKI,and VIP Chinese Scientific and Technological Periodical Database.Trials were considered to be of high qualit... |
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| Keywords: | Chronic atrophy gastritis Traditional Chinese medicine Meta-analysis |
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