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胰腺炎相关性腹水诱导的大鼠胰腺病理学改变
引用本文:赵海剑,程若川,方向,张建淮,张喜成. 胰腺炎相关性腹水诱导的大鼠胰腺病理学改变[J]. 肝胆胰外科杂志, 2007, 19(6): 349-351
作者姓名:赵海剑  程若川  方向  张建淮  张喜成
作者单位:淮安市第二人民医院,普通外科,江苏,淮安,223002;昆明医学院第一附属医院,普通外科,云南,昆明,650032
摘    要:目的观察胰腺炎相关性腹水(pancreatitis associated ascetic fluid,PAAF)腹腔注射后引起的胰腺病理学改变。方法SD大鼠26只,随机分为急性出血坏死性胰腺炎组(acute hemorrhagic necrotic pancreatitis,AHNP)(AHNP组,n=10),生理盐水(normal saline,NS)组(NS组,n=8)以及PAAF组(n=8)。制备急性出血坏死性胰腺炎腹水后,腹腔注射到健康大鼠体内,7h后活杀,取胰腺进行光镜以及电镜观察。结果PAAF组胰腺病理改变表现为腺泡细胞完整,腺叶间隔略增宽。结论PAAF腹腔注射后引起的胰腺病理改变轻微。

关 键 词:胰腺炎  腹水  胰腺  病理学
文章编号:1007-1954(2007)06-0349-03
收稿时间:2007-01-22
修稿时间:2007-01-22

The pathological changes of pancreas in rats induced by pancreatitis associated with the correlative ascites
ZHAO Haitian,CHENG Ruochuan, FANG Xiang,et al.. The pathological changes of pancreas in rats induced by pancreatitis associated with the correlative ascites[J]. Journal of Hepatopancreatobiliary Surgery, 2007, 19(6): 349-351
Authors:ZHAO Haitian  CHENG Ruochuan   FANG Xiang  et al.
Affiliation:ZHAO Haitian,CHENG Ruochuan, FANG Xiang, et al.
Abstract:Objective To investigate the pathological changes of pancreas in rats after PAAF injection into their abdominal cavities.Methods Twenty-six SD rats were randomly divided into AHNP group(n=10),NS group(n=8) and PAAF group(n=8).PAAF was injected into SD rat's abdominal cavity.Seven hours later,SD rats were killed.The changes of pancreas were observed.Results Morphological examination demonstrated that the pancreatic acinar cells were good,and the space between glandulae of pancreas became wide in PAAF group.Conclusion The pathological changes of pancreas in PAAF group are slight.
Keywords:pancreatitis  ascetic fluid  pancreas  pathology  
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