| Effect of Cycloheximide on the Adaptive Response Induced by Low Dose Radiation |
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| 作者姓名： | CAILU LIUSHUZHENG |
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| 作者单位： | DepartmentofRadiationBiology,InstituteofRadiationMedicine,NormanBethuneUniversityofMedicalSciences,Ch |
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| 摘 要： | Human lymphocytes pre-exposed to 10 mGy or 50mGy of X-rays become less sensitive to subsequent large dose irradiation,exhibited lower rate of chromosome aberration than expected.This adaptive response could be inhibited by cycloheximide,a protein synthesis inhibitor for successive 2h period ranging from 0.5h before to 4h after the low dose exposure,indicating that the adaptive response was directly related with the protein synthesis.
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| 关 键 词： | 低剂量辐射 诱导 适应性反应 环己酰亚胺 影响 |
Effect of cycloheximide on the adaptive response induced by low dose radiation. |
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| CAILU LIUSHUZHENG.Effect of Cycloheximide on the Adaptive Response Induced by Low Dose Radiation[J].Biomedical and Environmental Sciences,1992,5(1):46-52. |
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| Authors: | L Cai S Liu |
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| Institution: | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, China. |
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| Abstract: | Human lymphocytes pre-exposed to 10 mGy or 50 mGy of X-rays become less sensitive to subsequent large dose irradiation, exhibited lower rate of chromosome aberration than expected. This adaptive response could be inhibited by cycloheximide, a protein synthesis inhibitor for successive 2 h period ranging from 0.5h before to 4h after the low dose exposure, indicating that the adaptive response was directly related with the protein synthesis. |
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