脑外伤患者伤后血糖变化与预后的相关性研究

目的对脑外伤患者血糖水平变化及预后的相关性进行分析。方法选取来我院就诊的脑外伤患者112例作为研究对象,以其入院时的格拉斯哥昏迷评分(GCS)为依据将其分为轻度组(n=42)、中度组(n=40)、重度组(n=30),患者均在入院后第1天、第3天、第5天及第7天进行空腹血糖检测;按患者入院后第1天空腹血糖水平进行分组:空腹血糖<10 mmol/L组(n=85),≥10 mmol/L组(n=27),对两组患者的预后进行比较。结果三组患者入院后第1天空腹血糖水平明显负相关于GCS评分(P<0.05);重度组入院第1天的空腹血糖水平与中度组、轻度组比较明显升高(P<0.05);各组患者的空腹血糖水平随着治疗时间的延长出现降低。<10 mmol/L组中GCS 5分的患者所占比例明显高于≥10 mmol/L组,GCS患者所占的比例明显低于≥10 mmol/L组,两组比较均具有显著性差异(P<0.05)。结论通过定期检测脑外伤患者的空腹血糖,可以更好地了解患者的预后,对临床治疗具有指导意义。

Study on the correlation between changes in blood glucose and the prog- nosis of the patients with traumatic brain injury

Objective To analyze the correlation between changes of blood glucose level in patients with traumatic brain injury and prognosis. Methods A total of 112 cases with traumatic brain injury were selected from our hospital as the research object, they were divided into groups with its admission Glasgow coma score （GCS）： the mild group （n = 42）, the moderate group （n = 40）, severe group （n = 30）, fasting blood glucose were detected on first day after admis- sion, third day, fifth day and seventh day. They were grouped according to the blood glucose level of first day： the fasting blood glucose 〈10 mmol/L group （n = 85）, ≥ 10 mmol/L group （n = 27）, the outcomes were compared of two groups. Results Three groups of patients after admission glucose level was obvious negatively related to GCS score （P 〈 0.05）; Compared with moderate group and mild group, fasting blood glucose levels of severe group on the first day was significantly higher, there was significant difference （P 〈 0.05）; Each group of patients with fasting blood glucose level with the extension of treatment time decreased. The proportion of GCS 5 score in 〈10 mmol/L was significantly higher than that in ≥ 10 mmol/L group, the proportion of 1 score was significantly lower than that in ≥ 10 mmol/L group, two groups were significantly different （P 〈 0.05）. Conclusion Patients with traumatic brain injury by regular inspection of fasting blood glucose, can better understand the prognosis of the patients, which has guiding significance to the clinical treatment.