腹腔镜手术配合米非司酮治疗子宫内膜异位症疗效观察

目的探讨腹腔镜手术配合米非司酮治疗子宫内膜异位症的疗效。方法选择2010年5月～2011年4月在我院治疗的子宫内膜异位患者80例作为研究对象。80例患者根据治疗方法不同分为研究组和对照组各40例，两组均于月经干净后3～5d进行腹腔镜手术。观察组术后第5天开始口服米非司酮12．5mg，每日1次；连用3个月。比较两组疗效及两组患者停药后排卵、月经恢复时间。结果研究组临床完全缓解率80．0％，明显高于对照组的50．0％，且研究组6个月后复发率5．0％，明显低于对照组的20％，差异有统计学意义（P〈0．05）。研究组排卵恢复时间明显快于对照组，研究组月经恢复时间明显快于对照组，差异有统计学意义（P〈0．05）。结论腹腔镜手术配合米非司酮治疗子宫内膜异位症疗效显著，值得推广和应用。

Effect of laparoscopic surgery with mifepristone on treatment of endometriosis

Objective To investigate the laparoscopic surgery with the efficacy of mifepristone to treat endometriosis. Methods From May April 2010 to 2011 endometriosis treatment in our hospital 80 patients were selected for the study. 80 patients were divided into the study group and the control group, 40 cases in each treatment, the two groups are in menstrual clean 3-5 d after laparoscopic surgery. Observation group five days after the start of oral mifepristone 12.5 mg, twice daily, once every 3 months. The two groups were compared the efficacy and the two groups of patients after stopping ovulation, menstruation recovery time. Results The study group clinical complete remission rate, was 80.0%, significantly higher than that in the control group 50.0%, hut the study group recurrence rate of 5.0%, significantly lower than the control group 20%, the difference was statistically significant （P 〈 0.05）. Ovulation recovery time of study group was significantly faster than the control group, the study group menstruation recovery time was significantly faster than the control group, the difference was statistically significant （P 〈 0.05）. Conclusion Laparoscopic surgery with mifepristone treatment of endometriosis significant effect, worthy of promotion and application.