三七总皂苷与特利加压素联合治疗肝硬化腹水的效果观察

目的探讨肝硬化腹水患者采用三七总皂苷联合特利加压素进行治疗的临床效果。方法研究对象为来我院就诊的84例肝硬化腹水患者,按治疗方法不同分为对照组和观察组,分别给予综合治疗方法、三七总皂苷联合特利加压素共同治疗。对两组患者临床治疗效果、症状及体征、肝肾功能及各项肝纤维化观察指标进行比较。结果观察组患者的总有效率与对照组比较明显较高（P〈0．05）;观察组治疗8周后更好的改善了腹胀、腹水及肝区痛等临床症状体征,与对照组比较差异具有显著的统计学意义（P〈0．05）。两组患者治疗6～8周后,肝纤维化各项指标均明显降低,但观察组下降幅度更为明显（P〈0．05）。结论肝硬化腹水患者采用三七总皂苷联合特利加压素进行治疗能够使患者的临床症状得到显著的改善,效果较为满意,可以在临床推广应用。

Observation of cirrhosis ascites treated with panax notoginseng saponins combined with terlipressin

Objective To investigate saponins and terlipressin. Methods A the clinical effect of cirrhosis ascites total of 84 patients with ascites due to patients treated with panax notoginseng cirrhosis patients were selected from our hospital, they were divided into the observation group and the control group, were given comprehensive treatment method, panax notoginseng saponins combined with terlipressin treatment. We compared the clinical effect of the treat- ment group, two patients with symptoms and signs, liver function and the liver fibrosis indexes. Results The total ef- fective rate in the observation group compared with the control group was significantly higher （P 〈 0.05）, the observa- tion group after 8 weeks treatment compared with control group had better improvement of clinical symptoms and signs of abdominal distension, ascites and liver area pain, the difference was significant （P 〈 0.05）. After two groups treated 6-8 weeks, the indexes of hepatic fibrosis were obviously decreased, the observation group decreased more obvi- ously （P 〈 0.05）. Conclusion Patients with cirrhosis and ascites by panax notoginseng saponins combined with terli- pressin therapy can make the patient＇s clinical symptoms improved significantly, the effect is relatively satisfactory, can be widely used in clinical practice.