永冲595染料激光治疗生殖器尖锐湿疣的临床疗效分析

目的评价脉冲595染料激光治疗生殖器尖锐湿疣的临床疗效及安全性。方法将96例生殖器尖锐湿疣患者随机分为治疗组与对照组，每组48例。治疗组采用脉冲595染料激光治疗．对照组采用咪喹莫特乳膏治疗。治疗后随访3个月，比较两组治疗后的一次性治愈率与复发率。结果治疗组的一次性治愈率与复发率分别为79．17％（38／48）、20．83％（10／48）；而对照组的一次性治愈率与复发率分别为52．08％（25，48）、47．92％（23／48），两组比较差异有统计学意义（P〈0．05）。治疗组没有出现明显不良反应，而对照组的不良反应发生率为64．58％（31／48）。结论595染料激光治疗生殖器尖锐湿疣的临床疗效显著，复发率底，安全性高，值得推广。

Clinical efficacy of 595nm pulsed dye laser in the treatment of genital warts

Objective To evaluate the clinical effect and security of 595nm pulsed dye laser for the treatment of genital warts. Methods A total of 96 patients with genital warts were randomly divided into treatment group and control group, 48 cases per group. Patients in treatment group were treated by 595 nm pulsed dye laser and patients in control group were treated by imiquimod cream. One-time cure rate and recurrence rate were compared after follow-up for three months. Results The one-time cure rate and recurrence rate of treatment group was 79.17% （38/48）, 20.83% （10/48）, respectively and the one-time cure rate and recurrence rate of control group was 52.08% （25/48）, 47.92% （23/48）, respectively. There were significant differences between treatment group and control group （P 〈 0.05）. There were no ADRs in treatment group, but the occurrence rate of ADRs in control group was 64.58% （31/48）. Conclusion The clinical effect of 595nm pulsed dye laser in the treatment of genital warts is significant, and has low recurrence rate and high security; it is worthy to be popularized.