| 单肺通气的肺损伤机制及其保护性策略研究 |
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| 引用本文： | 宋正杰,林栓同,程静林,李治松. 单肺通气的肺损伤机制及其保护性策略研究[J]. 实用临床医药杂志, 2021, 25(2): 101-105,111. DOI: 10.7619/jcmp.20200435 |
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| 作者姓名： | 宋正杰 林栓同 程静林 李治松 |
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| 作者单位： | 郑州大学第二附属医院麻醉科,河南郑州,450016;山东省泰安市立医院手术麻醉中心,山东泰安,271000;郑州大学第二附属医院麻醉科,河南郑州,450016;郑州大学第二附属医院麻醉科,河南郑州,450016 |
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| 摘 要： | 单肺通气(OLV)在心胸外科已广泛应用,优势显而易见,但由此导致的肺损伤也不容忽视.OLV对呼吸生理的改变,加之术中体位、重力作用、操作等的影响,可使患者发生通气/血流比例失衡、炎症应激反应、低氧血症、肺不张等并发症.肺保护性通气能显著减轻机械通气相关性肺损伤,但影响肺保护性通气策略的临床应用效果的因素众多.本综述对O...
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| 关 键 词： | 单肺通气 肺损伤 保护性通气 呼气末正压 肺复张 |
Study on lung injury mechanism of one-lung ventilation and its protective strategy |
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| SONG Zhengjie,LIN Shuantong,CHENG Jinglin,LI Zhisong. Study on lung injury mechanism of one-lung ventilation and its protective strategy[J]. Journal of Clinical Medicine in Practice, 2021, 25(2): 101-105,111. DOI: 10.7619/jcmp.20200435 |
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| Authors: | SONG Zhengjie LIN Shuantong CHENG Jinglin LI Zhisong |
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| Affiliation: | (Department of Anesthesiology,Second Affiliated Hospital of Zhengzhou University,Zhengzhou,Hennan,450016;Surgical Anesthesia Center,Tai′an Municipal Hospital in Shandong Province,Tai′an,Shandong,271000) |
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| Abstract: | One lung ventilation(OLV)has been widely used in cardio-thoracic surgery,and has obvious advantages.However,lung injury caused by OLV has gradually attracted the attention of clinicians.Changes of respiration by OLV,and effects of intraoperative posture,gravity,and manipulation in operation lead to complications such as imbalance of ventilation to blood flow ratio,inflammatory stress reaction,hypoxemia,atelectasis and so on.Protective lung ventilation can significantly relieve lung injury related to ventilation,but there are many factors affecting the successful clinical application of lung protective ventilation strategies.In this paper,the progresses in pathogenesis and protective strategies of OLV-related lung injury were summarized to provide better strategies for patients in perioperation. |
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| Keywords: | one-lung ventilation lung injury protective ventilation positive end-expiratory pressure alveolar recruitment |
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