温和灸联合药物治疗呼吸机相关性肺炎的疗效观察

目的 观察温和灸联合药物治疗呼吸机相关性肺炎的临床疗效.方法 将66例符合标准的患者随机分为对照组和观察组,每组33例.对照组予常规治疗,观察组在对照组的治疗基础上另予温和灸治疗.观察两组临床肺部感染评分(CPIS)、动脉血氧分压(PaO2)及二氧化碳分压(PaCO2)的变化,比较两组机械通气时间、肺部感染控制时间及住...

Observations on the Efficacy of Combined Gentle Moxibustion and Medicine for Ventilator-associated Pneumonia

Objective To observe the clinical efficacy of gentle moxibustion for ventilator-associated pneumonia.Method Sixty-six patients meeting the diagnostic criteria were randomized to a control group and an observation group,33 cases in each group.The control group received conventional treatment and the observation group received gentle moxibustion in addition.The clinical pulmonary infection score(CPIS)was recorded and arterial oxygen partial pressure(PaO2)and carbon dioxide partial pressure(PaCO2)were measured in the two groups.Mechanical ventilation time,pulmonary infection control time and hospitalization time were compared between the two groups.Serum soluble triggering receptor expressed on myeloid cells-1(sTREM-1)and procalcitonin(PCT)levels were measured.The clinical therapeutic effects were evaluated in the two groups.Result After treatment,the total efficacy rate was significantly higher in the observation group than in the control group(P<0.05);the CPIS scores decreased in the two groups compared with those before treatment(P<0.05)and were lower in the observation group than in the control group(P<0.05);PaO2 and PaCO2 improved significantly in the observation group compared with those before treatment(P<0.05)and improved more than those in the control group(P<0.05);mechanical ventilation time,pulmonary infection control time and hospitalization time were shorter in the observation group than those in the control group(P<0.05);sTREM-1 and PCT levels decreased significantly in the observation group(P<0.05)and were lower than those in the control group(P<0.05).Conclusion Conventional treatment-based gentle moxibustion has a marked therapeutic effect on ventilator-associated pneumonia.It can reduce lung infection,improve PaO2 and PaCO2,shorten mechanical ventilation time,pulmonary infection control time and hospitalization time and decrease sTREM-1 and PCT levels.