Line-field parallel swept source MHz OCT for structural and functional retinal imaging |
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| Authors: | Daniel J. Fechtig Branislav Grajciar Tilman Schmoll Cedric Blatter Rene M. Werkmeister Wolfgang Drexler Rainer A. Leitgeb |
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| Affiliation: | 1Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria;2Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Austria;3Carl Zeiss Meditec, Inc., 5160 Hacienda Drive, Dublin, CA 94568, USA |
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| Abstract: | We demonstrate three-dimensional structural and functional retinal imaging with line-field parallel swept source imaging (LPSI) at acquisition speeds of up to 1 MHz equivalent A-scan rate with sensitivity better than 93.5 dB at a central wavelength of 840 nm. The results demonstrate competitive sensitivity, speed, image contrast and penetration depth when compared to conventional point scanning OCT. LPSI allows high-speed retinal imaging of function and morphology with commercially available components. We further demonstrate a method that mitigates the effect of the lateral Gaussian intensity distribution across the line focus and demonstrate and discuss the feasibility of high-speed optical angiography for visualization of the retinal microcirculation.OCIS codes: (110.4500) Optical coherence tomography, (170.0110) Imaging systems, (170.3880) Medical and biological imaging, (170.4460) Ophthalmic optics and devices |
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