Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model |
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| Authors: | Elizaveta Kon Giuseppe Filardo Marco Delcogliano Milena Fini Francesca Salamanna Gianluca Giavaresi Ivan Martin Maurilio Marcacci |
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| Affiliation: | (1) Biomechanics Laboratory-Rizzoli Orthopaedic Institute, Bologna, Italy;(2) Laboratory of Preclinical and Surgical Studies-Rizzoli Orthopaedic Institute, Bologna, Italy;(3) University Hospital Basel, Basel, Switzerland |
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| Abstract: | Background Current research aims to develop innovative approaches to improve chondral and osteochondral regeneration. The objective of this study was to investigate the regenerative potential of platelet-rich plasma (PRP) to enhance the repair process of a collagen-hydroxyapatite scaffold in osteochondral defects in a sheep model. |
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