| Detection of Hantavirus gene from peripheral blood of patients with HFRS in Heilongjiang province and the epidemiological significance |
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| 引用本文： | HUAN YONG CHEN,LING LAN ZENG,XIN ZHANG,HONG QI JIANG,FENG JUAN SHAO,QING GANG LI,BAO LING LU and LIN LI Department of Infectious Diseases,Department of Clinical Laboratory,the First Hospital of Harbin Medical University,Harbin,P. R . China Infectious Diseases Department,Wuhan Union Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan,P. R . China. Detection of Hantavirus gene from peripheral blood of patients with HFRS in Heilongjiang province and the epidemiological significance[J]. 中华微生物学和免疫学杂志(英文版), 2006, 4(4): 290-293 |
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| 作者姓名： | HUAN YONG CHEN LING LAN ZENG XIN ZHANG HONG QI JIANG FENG JUAN SHAO QING GANG LI BAO LING LU and LIN LI Department of Infectious Diseases Department of Clinical Laboratory the First Hospital of Harbin Medical University Harbin P. R . China Infectious Diseases Department Wuhan Union Hospital Tongji Medical College of Huazhong University of Science and Technology Wuhan P. R . China |
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| 作者单位： | HUAN YONG CHEN，LING LAN ZENG，XIN ZHANG，HONG QI JIANG，FENG JUAN SHAO，QING GANG LI，BAO LING LU and LIN LI Department of Infectious Diseases，Department of Clinical Laboratory，the First Hospital of Harbin Medical University，Harbin，P. R . China Infectious Diseases Department，Wuhan Union Hospital，Tongji Medical College of Huazhong University of Science and Technology，Wuhan，P. R . China |
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| 摘 要： | The aim of this study is to further understand the genotype of Hantavirus(HV) from peripheral blood of patients with hemorrhagic fever with renal syndrome (HFRS) and the epidemiological significance of this disease in Heilongjiang province in recent years. Thirty-one serum samples of clinically diagnosed patients with HFRS were examined by RT-PCR to decide the genetic subtype. On the basis of infection season, the serum samples were divided into two groups: winter (Nov, 2003—Feb, 2004) , spring and summer (April, 2004—Sep, 2004). Further analysis was performed in combination with clinical symptoms. It was found that among the total 31 samples, 22 were sero-positive. Among 14 serum samples in winter, 8 were sero-positive, of which 5 cases were of typeⅠ(Hantaan virus, HTNV) and 3 of typeⅡ(Seoul virus, SEOV). Among 17 samples in spring and summer, 14 were sero-positive, of which 5 cases were of typeⅠand 9 of typeⅡ. So it concludes that both of the two types of Hantavinis exist in Heilongjiang. The typeⅠis the main pathogen of HFRS in winter, and typeⅡis the main in spring and summer.
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| 关 键 词： | 黑龙江 出血热 肾病综合征 HFRS 外周血 汗坦病毒基因 检测 流行病学 |
Detection of Hantavirus gene from peripheral blood of patients with HFRS in Heilongjiang province and the epidemiological significance |
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| HUAN YONG CUEN LING LAN ZENG XIN ZHANG HONG QI JIANG FENG JUAN SHAO QING GANG LI BAO LING LU LIN LI. Detection of Hantavirus gene from peripheral blood of patients with HFRS in Heilongjiang province and the epidemiological significance[J]. Chinese Journal of Microbiology and Immunology, 2006, 4(4): 290-293 |
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| Authors: | HUAN YONG CUEN LING LAN ZENG XIN ZHANG HONG QI JIANG FENG JUAN SHAO QING GANG LI BAO LING LU LIN LI |
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| Affiliation: | [1]Department of Infectious Diseases, the First Hospital of Harbin Medical University, Harbin, P. R. China [2]Department of Clinical Laboratory, the First Hospital of Harbin Medical University, Harbin, P. R. China [3]Infectious Diseases Department, Wuhan Union Hospital, Ton~i Medical College of Huazhong University of Science and Technology, Wuhan, P. R. China |
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| Abstract: | |
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| Keywords: | Hantavirus Hemorrhagio fever with renal syndrome (HFRS) Epidemiology Genotype |
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