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用紫外分光光度法测定乙醇溶液中依沙吖啶的含量
引用本文:李中,刘雪梅,陈兆军.用紫外分光光度法测定乙醇溶液中依沙吖啶的含量[J].中国实用医药,2009,4(27):65-66.
作者姓名:李中  刘雪梅  陈兆军
作者单位:辽宁省大连市儿童医院药剂科,116027
摘    要:目的建立紫外分光光度法测定乙醇溶液中依沙吖啶含量的方法。方法以乙醇为溶剂,在370nm波长处测定溶液的吸光度,计算依沙吖啶的含量。结果在5μg/ml-15μg/ml的范围内吸光度与浓度之间具有良好的线性关系(r=0.9985),平均回收率为100.8%,RSD为1.16%(n=4)。结论该方法方便可靠,可以用于医院制剂的质量控制。

关 键 词:依沙吖啶  紫外分光光度法  含量测定

Determine the Contend of Ethacridine in Ethanol Solution by UV Spectrophotometric Method
LI Zhong,LIU Xue-mei,CHEN Zhao-jun.Determine the Contend of Ethacridine in Ethanol Solution by UV Spectrophotometric Method[J].China Practical Medical,2009,4(27):65-66.
Authors:LI Zhong  LIU Xue-mei  CHEN Zhao-jun
Institution:(Dalian pediatrics hospital Liaoning 116027, China)
Abstract:Objective To establish method for determining the content of ethacridine in ethanol solution by UV spectrophotometric method. Methods To determine the Abs of ethacridine in ethanol solution at 370nm; then calculate the content of ethacridine. Results There was good linear relationship between Abs and concentration of ethacridine (r = 0. 9985 ) ranging from 5μg/ml - 15μg/ml, with a average recovery rate of 100. 8% and RSD 1.16 percent (n =4). Conclusion This method is reliable enough for quality control of hospital preparation.
Keywords:Ethacridine  UV Spectrophotometric Method  Content determination
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