胸腰椎压缩性骨折经椎体后凸成形置入新型人工合成骨与骨水泥填充物的生物力学性能分析

 目的 应用三维有限元分析法比较两种材料置入青壮年正常骨质胸腰椎压缩性骨折的生物力学效应。方法 (1)测量两种材料铸件的力学性质;(2)建立青壮年正常骨质胸腰段的三维有限元模型;(3) 模拟L₁椎体后凸成形术后骨水泥强化并进行分析。结果 (1)成功建立正常骨质患者胸腰段三维有限元力学模型;(2)采用两种材料作为填充物均能重建椎体的稳定性，又不显著增加邻近节段椎间盘的应力。结论 新型人工合成骨(GENEX)未来可以作为治疗青壮年正常骨质胸腰椎压缩性骨折的一种理想的填充材料。

Casting mechanical characteristics of Genex and polymethyl mechacrylate aspercutaneous kyphoplasty fillers in treating unosteoporotic vertebral compressive fractures by 3D finite element analysis

Objective To compare the biological effects of polymethyl mechacrylate(PMMA)and calcium phosphate cement(CPC)as percutaneous kyphoplasty (PKP) fillers in treating osteoporotic vertebral compressive fractures by 3D finite element analysis.Methods (1)The casting mechanicaI characters of PMMA and CPC were measured.(2) the 3D finite element models were developed by using finite element software and others.(3) PKP was simulated to evaluate the influence of L₁.Results (1) A 3D finite element model of human osteoporotic thoracolumber spine was developed.(2) Injection of PMMA or CPC all could stabilize vertebrae and restore the strength and stifness of vertebral body and lead to less increase the stress concentration at its posterior body and adjacent vertebral body.Conclusion The new artificial bone (GENEX) in the future can be used as an ideal filling material for the treatment of thoracolumbar vertebral compression fracture in young adults.