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围绝经期综合征中医证素与性激素水平的相关研究
引用本文:杨敏,李灿东,李红,梁文娜.围绝经期综合征中医证素与性激素水平的相关研究[J].中华中医药杂志,2012(2):366-368.
作者姓名:杨敏  李灿东  李红  梁文娜
作者单位:福建中医药大学;福建省立医院
基金项目:国家自然科学基金资助项目(No.30772697);福建省教育厅资助项目(No.JA10164);福建省自然科学基金项目(No.2010J01130)~~
摘    要:目的:探讨围绝经期综合征常见中医证素与性激素水平的相关性。方法:选择174例围绝经期综合征患者,采用辨证要素积分的方法,通过对围绝经期综合征患者性激素指标的观察,研究围绝经期综合征中医证素与性激素水平的相关性。结果:①围绝经期综合征的病位证素主要以肝、肾为主;病性证素以阴虚、气滞、血虚为最多见;②E2与肾、血虚呈负相关;FSH与肾、血虚呈正相关;FSH/LH与肝、气滞呈正相关。结论:E2下降、FSH升高是肾虚形成的病理生理学基础之一,FSH/LH与肝郁密切相关。

关 键 词:围绝经期综合征  证素  性激素

Correlational study on TCM syndrome elements and sex hormones in perimenopausal syndrome
YANG Min,LI Can-dong,LI Hong,LIANG Wen-na.Correlational study on TCM syndrome elements and sex hormones in perimenopausal syndrome[J].China Journal of Traditional Chinese Medicine and Pharmacy,2012(2):366-368.
Authors:YANG Min  LI Can-dong  LI Hong  LIANG Wen-na
Institution:YANG Min1,LI Can-dong1,LI Hong2,LIANG Wen-na1(1Fujian University of TCM,Fuzhou 350108,China;2Fujian Provincial Hospital,Fuzhou 350003,China)
Abstract:Objective: To disscus the relevance of TCM syndrome elements and sex hormones in perimenopausal syndrome.Methods: Choosing 174 perimenopausal syndrome patients,using the method of differentiation of syndrome elements,through the observation of sex hormones,to research relevance of TCM syndrome elements and sex hormones.Results: ①The main locations of perimenopausal syndrome are liver and kidney;Yin deficiency,Qi stagnation and blood deficiency are the main nature of disease.②E2 is negatively related to kidney and blood deficiency;FSH is positively related to kidney and blood deficiency;FSH/LH is positively related to liver and Qi stagnation.Conclusion: The decline of E2 and increase of FSH is one of the pathophysiological basis of deficiency of kidney,FSH/LH is closely related to the liver depression.
Keywords:Perimenopausal syndrome  Syndrome element  Sex hormone
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