| 猫耳刺中三萜类化合物的结构研究 |
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| 引用本文： | 谢光波,周思祥,雷连娣,屠鹏飞,. 猫耳刺中三萜类化合物的结构研究[J]. 中国中药杂志, 2007, 32(18): 1890-1892 |
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| 作者姓名： | 谢光波 周思祥 雷连娣 屠鹏飞 |
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| 作者单位： | 1. 北京大学,药学院,天然药物学系,北京,100083
2. 北京大学,药学院,天然药物学系,北京,100083;中国协和医科大学,中国医学科学院,药用植物研究所,北京,100094 |
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| 基金项目： | 国家自然科学基金;高校长江学者及创新团队计划 |
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| 摘 要： | 目的：研究猫耳刺Ilex pernyi叶的化学成分。方法：应用硅胶及Sephadex LH-20凝胶柱色谱法对其化学成分进行分离,并利用NMR和MS等方法鉴定分离得到的化合物。结果：从猫耳刺的干燥叶中分离得到8个三萜化合物,分别鉴定为熊果酸(1),羽扇豆醇(2),α-香树脂醇(3),熊果醇(4),3β-羟基-乌索-11-烯-28,13β-内酯(5),坡模酸(6),羽扇-20(29)-烯-3β,24-二醇(7),3β,23-二羟基乌索-12-烯-28-酸(8),结论：该8个化合物均为首次从猫耳刺中分离得到。
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| 关 键 词： | 冬青属 猫耳刺 化学成分 三萜 |
| 文章编号： | 1001-5302（2007）18-1890-03 |
| 收稿时间： | 2006-03-14 |
| 修稿时间： | 2006-03-14 |
Studies on triterpenoid constituents in leaf of Ilex pernyi |
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| XIE Guang-bo; ZHOU Si-xiang;; LEI Lian-di; TU Peng-fei. Studies on triterpenoid constituents in leaf of Ilex pernyi[J]. China Journal of Chinese Materia Medica, 2007, 32(18): 1890-1892 |
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| Authors: | XIE Guang-bo ZHOU Si-xiang LEI Lian-di TU Peng-fei |
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| Affiliation: | Department of Natural Medicines, School of Pharmaceutical Sciences,Peking University, Beijing 100083, China. |
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| Abstract: | OBJECTIVE: To investigate the chemical constituents of Ilex pernyi. METHOD: The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data. RESULT: Eight triterpenoid compounds were isolated and identified as ursolic acid (1), lupeol (2), alpha-amyrin (3), uvaol (4), 3beta-hydroxyurs-11-ene-13beta-olide (5), pomolic acid (6), lup-20 (29)-ene-3beta, 24-diol (7), 3beta, 23-dihydroxy-urs-12-en-28-oic acid (8). CONCLUSION: The eight compounds were obtained from this plant for the first time. |
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| Keywords: | Ilex Ilex pernyi chemical constituents tirterpenoids |
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