微粒活性炭标记胃癌根治术

目的：探讨通过微粒活性炭标记提高胃癌根治术淋巴结清除彻底性的意义。方法：57例胃癌病人随机分为注墨组、对照组。注墨组病人术前胃镜下癌周注入吸附抗癌药物的微粒活性炭MMC－CH40，术中根据被MMC－CH40染黑的淋巴结作为清除标志，行胃癌根治术。对照组行R2、R3根治切除术。结果：（1）平均每例清除淋巴结数：注黑组41．5个，对照组24．4个（P＜0．05）。（2）注墨组黑染淋巴结数占清除淋巴结总数的67．1％。（3）淋巴结转移阳性的病例中，注墨组平均每例清除转移淋巴结数10．05个，对照组6．74个（P＜0．05）。（4）术前1周内胃镜下注墨，术中均可得到满意数量的黑染淋巴结。结论：术前胃镜下注入微粒活性炭对提高胃癌根治切除术中淋巴结清除的彻底性有指导意义。

Radical operation of gastric cancer with labelling MMC-CH40

Objective:To explore the clinical significance of labelling MM C-CH 40 in the radical operation of gastric cancer.Methods:Fifty seven patients with gastric cancer were randomly divided into two groups-labelling group and control group.In the labelling group,MM C-CH 40 was injected into the periphery of tumor through gastroscope before operation,then performed radical gastrectomy,the dyed lymph nodes were regarded as marker of the operation.Results:(1)In the labelling group,the average number of eliminated lymph nodes(41.5) was far higher than that of control group (24.4).(2)In the labelling group,of the total eliminated lymph nodes,dyed lymph nodes were 67.1%.(3)In the case of lymph node metastasis,the average number eliminated in the labelling group was 10.05,and that of the control group was 6.74.(4) Inject MM C-CH 40 into the periphery of tumor through gastroscope one week before operation could get a satisfactory result.Conclusion:MM C-CH 40 labelled lymph nodes can guide the radical gastrectomy.