Estimation of thyroid gland volume by spiral computed tomography |
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| Authors: | R Hermans R Bouillon K Laga P R Delaere B De Foer G Marchal A L Baert |
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| Institution: | (1) Department of Radiology, University Hospitals, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium, BE;(2) Department of Endocrinology, University Hospitals, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium, BE;(3) Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium, BE |
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| Abstract: | The objective of this study was to test the accuracy of CT for the estimation of the volume of enlarged thyroid glands. An
unenhanced spiral CT scan of neck and upper mediastinum was obtained in 36 patients with an enlarged thyroid gland. By manual
segmentation the surface of the thyroid gland on 5-mm-thick slices was calculated; these surfaces were multiplied by the slice
interval (10 mm) and summated to obtain the volume of the gland. All patients underwent a total or subtotal thyroidectomy.
1 cm3 of thyroid gland tissue was considered to weigh 1 g. A good correlation was found between the volume estimated by CT and
the weight at pathological examination of the resected gland (r = 0.98, p < 0.001), with a mean difference of + 12 % (range: + 57.3 to –13.9 %). The volume calculation is reproducible among different
observers (r = 0.99, p < 0.01). Computed tomography allows an easy, reliable and reproducible volume determination of enlarged thyroid glands.
Received 23 November 1995; Revision received 7 May 1996; Accepted 13 May 1996 |
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| Keywords: | : CT Thyroid abnormalities Image processing |
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