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某院471例抗精神病药物不良反应的分析
引用本文:向小妹,潘彬斌,卢荻朋.某院471例抗精神病药物不良反应的分析[J].中国医药指南,2013(3):436-437.
作者姓名:向小妹  潘彬斌  卢荻朋
作者单位:九江市第五人民医院药剂科,江西九江332000
摘    要:目的探讨我院抗精神病药物所致不良反应(ADR)的发生情况,为合理用药提供参考。方法收集我院2010年-2011年的471例抗精神病药物所发生的ADR报告,对患者性别、年龄、合并用药及不良反应临床表现等情况进行统计、分析。结果本院上报的抗精神病药物发生的不良反应主要发生在21~60岁;累及10个系统-器官,主要以神经系统不良反应(28.03%)及心血管系统不良反应(19.32%)最常见。结论医疗机构应重视抗精神病药引起的不良反应,加强抗精神病药的合理应用。

关 键 词:抗精神病药  不良反应(ADR)  分析  监测

Analysis of 471 Cases of Adverse Drug Reaction induced by Psychotic Drugs Reported in A Hospital
XIANG Xiao-mei,PAN Bin-bin,LU Di-peng.Analysis of 471 Cases of Adverse Drug Reaction induced by Psychotic Drugs Reported in A Hospital[J].Guide of China Medicine,2013(3):436-437.
Authors:XIANG Xiao-mei  PAN Bin-bin  LU Di-peng
Institution:XIANG Xiao-mei, PAN Bin-bin, L U Di-peng (Department of Pharmacy, No. 5 People's Hospital of Jiujiang, Jiujiang 332000, China)
Abstract:Objective To investigate the antipsychotic induced adverse drug reaction (ADR) occurred in our hospital, and provide advice for the rational use of drugs. Methods To conduct a statistical analysis based upon the information from 471 inpatients with ADR which were reported from 2010-2011 in my hospital such as gender, age, drug combination etc. Results ADR is likely to be reported in various ages section during inpatients, particularly those are 20-60 years old. It involves ten systems, will mainly cause the central nervous system damage (28.03%) and cardiovascular system (19.32%). Conclusion Medical institutions should pay attention to antipsychotic induced adverse and rational use of it .
Keywords:Antipsychotic drugs  Adverse drug reaction  Analysis  Testing
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