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Soluble urokinase-type plasminogen activator receptor levels in patients with burn injuries and inhalation trauma requiring mechanical ventilation: an observational cohort study
Authors:Yara Backes  Koenraad F van der Sluijs  Anita M Tuip de Boer  Jorrit Jan Hofstra  Alexander PJ Vlaar  Rogier M Determann  Paul Knape  David P Mackie  Marcus J Schultz
Affiliation:(1) Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands;(2) Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands;(3) Department of Anesthesiology, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands;(4) Department of Internal Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands;(5) Department of Anesthesiology, Rode Kruis Ziekenhuis, Brandwonden Centrum Beverwijk, Beverwijk, The Netherlands
Abstract:

Introduction  

Soluble urokinase-type plasminogen activator receptor (suPAR) has been proposed as a biologic marker of fibrinolysis and inflammation. The aim of this study was to investigate the diagnostic and prognostic value of systemic and pulmonary levels of suPAR in burn patients with inhalation trauma who need mechanical ventilation.
Keywords:
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