| 转人M受体亚型基因CHO细胞系在新 |
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| 引用本文： | 邱瑜,崔永耀,陈红专.转人M受体亚型基因CHO细胞系在新[J].中国新药杂志,2001,10(4):245-248. |
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| 作者姓名： | 邱瑜 崔永耀 陈红专 |
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| 作者单位： | 上海第二医科大学药理学教研室, |
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| 基金项目： | 国家自然科学基金项目（编号 30070860） |
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| 摘 要： | 综述了转人M受体亚型基因CHO细胞系在M受体亚型选择性新药筛选中的应用以及应用过程中应注意的问题，并对已筛选出的M受体亚型选择性激动剂和拮抗剂作简要介绍。
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| 关 键 词： | M受体 中国仓鼠卵巢细胞系 基因克隆 受体亚型 高通量药物筛选 M受体激动剂 M受体拮抗剂 |
| 文章编号： | 1003-3734(2001)04-0245-04 |
| 修稿时间： | 2000年4月26日 |
Application of human muscarinic receptor subtype gene transfection CHO cell line in new drug screening |
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| QIU Yu,Yong-yao,CHEN Hong-zhuan.Application of human muscarinic receptor subtype gene transfection CHO cell line in new drug screening[J].Chinese Journal of New Drugs,2001,10(4):245-248. |
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| Authors: | QIU Yu Yong-yao CHEN Hong-zhuan |
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| Abstract: | The application of CHO cell line transfected with human muscarinic receptor subtype gene in new drug screening and the factors which may confound the results were reviewed.In addition,the screened-out subtype-selective musearinic agonists and antagonists were also briefly introduced. |
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| Keywords: | muscarinic receptor Chinese hamster ovary cell line gene cloning receptor subtype high throughput screening muscarinic agonists muscarinic antagonists |
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