新生儿重症监护病房的院内感染临床分析

目的:探讨新生儿重症监护室院内感染的危险因素,指导院内感染防控。方法:对入住我科NICU的580份病例进行院内感染调查分析。结果:在580例新生儿中有71例发生了96次院内感染,院内感染率为12.2%,包括36例血流感染,33例肺炎,18例尿路感染,6例结膜炎及3例脐炎。最常见的病原菌是肺炎克雷伯杆菌(38.5%)和凝固酶阴性葡萄球菌(31.3%)。只有3例念珠菌引起的血流感染(8.3%)。结论:院内感染与住院天数、Apgar评分、低出生体重及菌株的耐药等因素有关,应加强管理和防范,降低新生儿院内感染率。

Clinical analysis of nosocomial infection in neonatal intensive care units

Objective To investigate the dangerous factors of nosocomial infection in neonatal intensive care units,in order to provide strategies for nosocomial infection control.Method Totally 580 newborn patients with nosocomial infection in neonatal intensive care units（NICU）of our hospital were retrospectively analyzed.Results Of the 580 neonates evaluated,71（12.2%）developed a total of 96 HAIs,including 36 bloodstream infections（BSIs）,33 pneumonias,18 urinary tract infections,6 conjunctivitis,and 3 onphalitis.Klebsiella pneumoniae（38.5%）and coagulase-negative staphylococci（31.3%）were the most frequently isolated microorganisms.Only 3 Candida spp determined BSIs（8.3%）.Conclusion Newborn nosocomial infection is related with multiple factors such as the duration of hospitalization,Apgar scores,lower birth weight and antibiotic-resistant of pathogens.So the management and prevention work should be enhanced to reduce nosocomial infection rate.