| 脂肪组织局部肾素血管紧张素系统与代谢综合征 |
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| 引用本文： | 叶菲,汤正义,宁光. 脂肪组织局部肾素血管紧张素系统与代谢综合征[J]. 国外医学:内科学分册, 2009, 36(2): 98-100 |
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| 作者姓名： | 叶菲 汤正义 宁光 |
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| 作者单位： | 上海交通大学医学院附属瑞金医院内分泌代谢病科,上海,200025;上海交通大学医学院附属瑞金医院内分泌代谢病科,上海,200025;上海交通大学医学院附属瑞金医院内分泌代谢病科,上海,200025 |
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| 摘 要： | 肾素-血管紧张素系统相关成分陆续在脂肪组织中发现，它们主要受能量代谢调节，与代谢综合征的发生发展有密切关系。在机体发生肥胖、高血压、高血糖和高胰岛素血症时，脂肪组织内肾素-血管紧张素系统表达增加；应用血管紧张素受体拮抗剂或血管紧张素转换酶抑制剂，通过改变脂肪细胞功能等作用，改善代谢综合征的状态。
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| 关 键 词： | 肾素-血管紧张素系统 脂肪组织 代谢综合征 |
The local renin-angiotensin system in adipose tissue and its relationship with metabolic syndrome |
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| YE Fei,TANG Zheng-yi,NING Guang. The local renin-angiotensin system in adipose tissue and its relationship with metabolic syndrome[J]. Foreign Medical Sciences(Section of Internal Medicine), 2009, 36(2): 98-100 |
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| Authors: | YE Fei TANG Zheng-yi NING Guang |
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| Affiliation: | YE Fei,TANG Zheng-yi,NING Guang. Department of Endocrinology,Shanghai Jiaotong University Affiliated Ruijin Hospital,Shanghai 200025,China |
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| Abstract: | The components of renin-angiotensin system （RAS） have been found in adipose tissue. They are mainly regulated by energy metabolism and closely related with metabolic syndrome. The expression of local RAS in adipose tissue is increased under the situation of obesity, hypertension, hyperglycemia, and hyperinsulinemia. These conditions of metabolic syndrome could be improved by the usage of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. |
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| Keywords: | Renin-angiotensin system Adipose tissue Metabolic syndrome |
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