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热灌注化疗联合深部热疗治疗恶性腹腔积液的疗效分析
引用本文:王艳丽,马少林,高英杰,李冬杰,孙砚诚,李贲. 热灌注化疗联合深部热疗治疗恶性腹腔积液的疗效分析[J]. 现代肿瘤医学, 2014, 0(5): 1159-1161
作者姓名:王艳丽  马少林  高英杰  李冬杰  孙砚诚  李贲
作者单位:[1]保定市第二中心医院,河北保定072750 [2]保定市第三医院,河北保定071000
摘    要:目的:总结深部热疗联合热灌注化疗治疗恶性腹腔积液的疗效。方法:将我院2012年01月-2012年10月56例恶性腹腔积液患者随机分成两组,一组单独给予顺铂腹腔内灌注化疗(单纯组),一组进行顺铂热灌注化疗联合深部热疗治疗(实验组),2个疗程后评价疗效。结果:热灌注化疗联合深部热疗治疗恶性腹腔积液总有效率(RR)为64.3%,单纯顺铂腹腔内灌注化疗组总有效率为32.1%,两组差异有统计学意义,P<0.05。热疗与化疗有良好的协同增效作用,且安全有效,毒副反应低。结论:热灌注化疗联合深部热疗治疗恶性腹腔积液疗效明显,已成为治疗恶性胸腹水的重要手段。

关 键 词:深部热疗  热灌注化疗  恶性腹腔积液

The effect of hyperthermia perfusion chemotherapy combined with deep thermotherapy in the treatment of malignant ascites
Wang Yanli,Ma Shaolin,Gao Yingjie,Li Dongjie,Sun Yancheng,Li Ben. The effect of hyperthermia perfusion chemotherapy combined with deep thermotherapy in the treatment of malignant ascites[J]. Journal of Modern Oncology, 2014, 0(5): 1159-1161
Authors:Wang Yanli  Ma Shaolin  Gao Yingjie  Li Dongjie  Sun Yancheng  Li Ben
Affiliation:1 The Second Central Hospital of Baoding ,Hebei Baoding 072750, China;2 The Third Hospital of Baoding ,Hebei Baoding 071000, China)
Abstract:Objective:To investigate the efficacy of intracavitary Perfusion chemotheraPy combined with deeP ther-motheraPy in the treatment of cancerous ascites. Methods:All 56 cases of malignant ascites Patients diagnosed in our hosPital from January 2012 to October 2012,were randomly divided into 2 grouPs. The simPle grouP was treated with CisPlatin infusion chemotheraPy,the exPerimental grouP was given CisPlatin Perfusion chemotheraPy combined with deeP hyPerthermia treatment. Efficacy of 2 grouPs were evaluated after two courses. Results:The total efficiency of exPerimental grouP given CisPlatin Perfusion chemotheraPy combined with deeP hyPerthermia treatment was 64. 3% , significantly higher than the simPle grouP,P ﹤ 0. 05. eyPerthermia and chemotheraPy have good synergies,and it is safe,effective and low toxicity. Conclusion:The effect of hyPerthermia Perfusion chemotheraPy combined with deeP thermotheraPy in the treatment of malignant ascites is good. It is an imPortant means for the treatment of malignant as-cites.
Keywords:deep hyperthermia  perfusion chemotherapy  malignant ascites
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