多民族静息心率与心血管危险因素的关系

目的了解新疆博尔塔拉州（博州）维吾尔族（维）、哈萨克族（哈）、蒙古族（蒙）、汉族人静息心率（HR）与心血管病（CVD）危险因素肥胖、高血压、高血糖、血脂紊乱的关系。方法利用2004年新疆博州维、哈、蒙、汉族代谢综合征的流行病学调查资料4335人（维、哈、蒙、汉各1248、1054、818、1215例），通过回归分析寻找静息HR和CVD危险因素的关系。结果随着静息HR增加，收缩压（SBP）、舒张压（DBP）、体重指数（BMI）、腹围（WC）、空腹血糖（FBG）、甘油三酯、总胆固醇、高密度脂蛋白水平及肥胖、高血压、高空腹血糖、血脂紊乱、≥3项CVD危险因素聚集检出率均有逐渐增高趋势（均P〈0．05）；应用多元线性和Logistic回归分析，和静息HR〈65次/min比较，静息HR〉85次／min者SBP、DBP分别增加8．9mmHg、4．1mmHg（P=0．000），高血压发生风险是1．82倍（95％CI1．45—2．28）；WC、BMI分别增加2．2cm、0．8kg／m^2（P=0．0130），肥胖风险是1．37倍（95％CI1．08～1．73）；FBG增加0．8mmol／L（P：0．000），高空腹血糖风险是2．77倍（95％CI2．13～3．59）；血脂紊乱风险是1．58倍（95％CI 1．26～1．97）；CVD危险因素≥3项聚集出现的风险是2．80倍（95％CI2．10～3．74）。结论新疆博州地区维、哈、蒙、汉族人群中随着静息心率的增加肥胖、高血压、高空腹血糖、血脂紊乱等多项心血管病危险因素发生风险增加，并且心血管病危险因素易聚集出现。

Association of resting heart rate with cardiovascular risk factors in several ethnical populations in XinJiang BOERTALA region

Objective To study the relationship between resting heart rate and cardiovascular dis-ease(CVD)risk factors in Uygur,Kazak,Mongolian,Han multiethnic populations.Methods The study sample comprised 4335 subjects(20-79years)(Uygur 1248,Kazak 1054,Mongolian 818,Han 1215) from the Xinjiang BOERTALA region by random cluster sampling.Association of resting heart rate with CVD risk factors was assessed by ANOVA and regression model.Results The prevalence of hypertension,obesity,high fasting blood glucose,dyslipidemia,≥3 components together and the average levels of systol-ic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),waist circumference (WC),fasting blood glucose(FBG),triglyceride(TG),total cholesterol(TC),high density lipoprotein-cholesterol(HDL-c)increased as resting heart rate increased(all of P<0.05).After adjustment for age,gender,ethnic,drinking,smoking with regression analysis,compared to the group with resting heart rate<65/min,SBP,DBP,WC,BMI,FBG increased 8.9mmHg(P=0.000),4.1mmHg(P=0.000),2.2cm(P=0.000),0.8kg/m~2(P=0.000),0.8mmol/L(P=0.000)respectively.And the odds ra-tios(Ors)of the prevalence of hypertension,obesity,high fasting blood glucose,dyslipidemia.≥3 com-ponents together were 1.82(95%CI 1.45～2.28),1.37(95%CI 1.08～1.73),2.77(95%CI 2.13～3.59),1.58(95%CI 1.26～1.97),2.80(95%CI 2.10～3.74)in the group with resting heart rate>85/min respectively.Conclusions Cardiovascular disease risk factors,such as obesity,hypertension,high fasting blood Glucose,and dyslipidemia,increased as resting heart rate increased among Uygur.Kaz-ak,Mongolian multiethnic populations.