Staging of palpable tl-2 invasive breast cancer with helical ct |
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Authors: | Takayoshi Uematsu Muneaki Sano Keiichi Homma Haruhiko Makino Makoto Shiina Shinichi Kobayashi Katsuhide Shimizu |
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Institution: | The Department of Radiology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Niigata-shi, Niigata 951-8566, Japan. |
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Abstract: | BACKGROUND: The purpose of this study was to evaluate the accuracy of contrast-enhanced high resolution helical computed tomography (CT) for assessing locoregional staging of palpable T1-2 invasive breast cancer. METHODS: Helical CT studies of 156 lesions from 156 patients with invasive breast cancer before breast-conserving surgery were examined. A lesion was defined as positive if focal enhancement was detected by CT within 100 seconds after contrast material administration. After resection, tumors were histopathologically mapped and comparison made with the extent of contrast enhancement. RESULTS: Helical CT enabled detection of all 156 index tumors. CT enabled detection of 28 of 43 multifocal lesions (65%) and five of five multicentric lesions (100%). In 24 of 33 lesions (73%), CT revealed additional cancers not seen on mammography. The extent of tumor significantly correlated with CT measurements (r=0.76, p<0.0001). CONCLUSION: Helical CT of the breast is an accurate preoperative imaging modality for assessing the locoregional staging of T1-2 invasive breast cancer. |
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Keywords: | Helical CT Breast cancer High-resolution CT Breast conserving surgery Intraductal extension |
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